SML3803
Gabapentin Enacarbil
≥95% (HPLC)
동의어(들):
1-[[(1-(Isobutanoyloxy)ethoxy)carbonyl]aminomethyl]cyclohex-1-ylacetic acid, 1-[[[[1-(2-Methyl-1-oxopropoxy)ethoxy]carbonyl]amino]methyl]cyclohexaneacetic acid, XP 13512
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C16H27NO6
CAS Number:
Molecular Weight:
329.39
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.21
추천 제품
Quality Level
분석
≥95% (HPLC)
양식
oil
색상
, Faint yellow to dark yellow
저장 온도
2-8°C
SMILES string
N(CC1(CCCCC1)CC(=O)O)C(=O)OC(OC(=O)C(C)C)C
InChI
1S/C16H27NO6/c1-11(2)14(20)22-12(3)23-15(21)17-10-16(9-13(18)19)7-5-4-6-8-16/h11-12H,4-10H2,1-3H3,(H,17,21)(H,18,19)
생화학적/생리학적 작용
Gabapentin enacarbil, a prodrug to gabapentin, is an orally available anticonvulsant and analgesic drug of the gabapentinoid class. Gabapentin enacarbil is used for treatment of restless legs syndrome.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: II. Improved oral bioavailability, dose proportionality, and colonic absorption compared with gabapentin in rats and monkeys
Journal of Pharmacology and Experimental Therapeutics, 311(1), 324-333 (2004)
Non-dopaminergic vs. dopaminergic treatment options in restless legs syndrome
Advances in Pharmacology, 84, 187-205 (2019)
Satomi Yamaguchi Ikeuchi et al.
Biological & pharmaceutical bulletin, 41(11), 1708-1715 (2018-11-02)
The purpose of this research was to establish an in vitro dissolution testing method to predict the oral pharmacokinetic (PK) profiles and food effects of gabapentin enacarbil formulated as wax matrix extended-release (ER) tablets in humans. We adopted various biorelevant
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