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Merck
모든 사진(1)

Key Documents

SRP6058

Sigma-Aldrich

Kallikrein-3 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

동의어(들):

APS, Hk3, KLK2A1, Kallikrein-3, P-30 antigen, PSA

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About This Item

CAS Number:
UNSPSC 코드:
12352202
NACRES:
NA.32

생물학적 소스

human

재조합

expressed in human cells

분석

≥95% (SDS-PAGE)

형태

lyophilized

분자량

35 kDa

포장

pkg of 20 μg

NCBI 수납 번호

배송 상태

dry ice

저장 온도

−70°C

유전자 정보

human ... KLK3(354)

일반 설명

Prostate-specific antigen, also known as Gamma-seminoprotein, Kallikrein-3, kallikrein-related peptidase 3, Semenogelase, KLK3 and PSA, is a secreted protein which belongs to thepeptidase S1 family and Kallikrein subfamily. KLK3/Kallikrein 3 contains one peptidase S1 domain. KLK3/Kallikrein 3 is a glycoprotein produced almost exclusively by the prostate gland. KLK3/Kallikrein 3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely.It is also believed to be instrumental in dissolving the cervical mucous, allowing the entry of sperm. Human KLK3/Kallikrein 3 and human KLK2 are closely related products of the human kallikrein genes KLK3 and KLK2, respectively. Both KLK3/Kallikrein 3 and human kallikrein 2 are produced and secreted in the prostate and have important applications in the diagnosis of prostate cancer. Understanding the mechanism by which genetic variation in KLK3/Kallikrein 3 affects prostate cancer risk has important implications for study of the biological role of KLK3/Kallikrein 3 in prostate tumorigenesis.

물리적 형태

Lyophilized from sterile PBS, pH 7.4. (Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.)

제조 메모

Centrifuge the vial prior to opening.

재구성

Detailed reconstitution instructions are sent along with the product.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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