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Merck
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T3526

Sigma-Aldrich

Anti-TUBA1B (alpha-tubulin ubiquitous) Antibody

rabbit polyclonal

동의어(들):

Anti-K-ALPHA-1

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모든 사진(2)

About This Item

MDL number:
MFCD00145921
UNSPSC 코드:
12352203
NACRES:
NA.41

제품명

Anti-Tubulin antibody produced in rabbit, whole antiserum

생물학적 소스

rabbit

Quality Level

200

결합

unconjugated

항체 형태

whole antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

포함

15 mM sodium azide

종 반응성

chicken, mouse

기술

indirect immunofluorescence: 1:80 using cultured fibroblasts
western blot: 1:200 using chicken gizzard extract or mouse brain extract

UniProt 수납 번호

P68363

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Tuba1b(22143) , Tubb2a(22151) , Tubb2b(73710) , Tubb2c(227613)

일반 설명

Microtubules are composed of tubulin and several additional proteins designated microtubule associated proteins (MAPs). Tubulin is a heterodimer which consists of an α-chain and a β-chain, both of which have a molecular weight of approximately 55,000. Microtubules form an elaborate cytoplasmic network during interphase and are reorganized into the mitotic spindle during cell division.
Tubulin is an extremely conserved and negatively charged protein. It is expressed in all eukaryotic cells, but mainly in brains.

특이성

The product stains tubulin in cultured chicken fibroblasts or 3T3 mouse fibroblasts. Additional bands may be stained in immunoblotting.

면역원

microtubule proteins from brains of 13 day old chicken embryos

애플리케이션

Anti-Tubulin antibody produced in rabbit has been used in immunoblotting and indirect immunofluorescence.

생화학적/생리학적 작용

αβ-tubulin heterodimers helps in formation of microtubules. Tubulin dimers exhibits GTPase activity, assembly and disassembly properties. It facilitates the construction of the flagellar apparatus.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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시험 성적서(COA)

Lot/Batch Number
0000359483
0000359483
0000237218
0000193757
038M4887V

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COA 검색

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문서 라이브러리 방문

Hong Zhu et al.
Experimental and therapeutic medicine, 15(3), 2643-2648 (2018-02-20)
The aim of the present study was to investigate the mechanism of action by which naringin reverses the resistance of ovarian cancer cells to cisplatin. Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) and western blotting assays were used to detect
Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: an in vitro model of HTLV-I-induced disease
Maldonado H, et al.
Biological Research, 41(3), 239-259 (2008)
Isolating tubulin from nonneural sources
Methods in Cell Biology, 95, 17-32 (2010)
Tubulin and microtubule structure
Downing KH and Nogales E
Current Opinion in Cell Biology, 10(1), 16-22 (1998)
Richard I Near et al.
Molecular vision, 15, 685-699 (2009-04-15)
AND-34/BCAR3 (Breast Cancer Anti-Estrogen Resistance 3) associates with the focal adhesion adaptor protein, p130CAS/BCAR1. Expression of AND-34 regulates epithelial cell growth pattern, motility, and growth factor dependence. We sought to establish the effects of the loss of AND-34 expression in
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문서

Antibodies to Tubulins, including Centrosome-Associated ε-Tubulin

Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of α- and β-tubulin. In addition to α-and β-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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