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Merck
모든 사진(1)

주요 문서

T9924

Sigma-Aldrich

Troponin I from human heart

lyophilized powder

동의어(들):

Tn-I

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.32

생물학적 소스

human heart

Quality Level

양식

lyophilized powder

정제법

affinity chromatography

기술

inhibition assay: suitable

solubility

water: 5 vial/mL, clear, colorless

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

유전자 정보

human ... TNNI3(7137)

애플리케이션

Troponin I from human heart can be used in studies whether the actin and aldolase can protect rabbit muscle lactate dehydrogenase inhibition by ascorbate or not.

생화학적/생리학적 작용

The inhibiting subunit of troponin, responsible for preventing actin-myosin binding and ATPase activity.
Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Nikita Sitkov et al.
Micromachines, 12(6) (2021-07-03)
The problems of chronic or noncommunicable diseases (NCD) that now kill around 40 million people each year require multiparametric combinatorial diagnostics for the selection of effective treatment tactics. This could be implemented using the biosensor principle based on peptide aptamers
M A Moses et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(6), 2645-2650 (1999-03-17)
Cartilage is an avascular and relatively tumor-resistant tissue. Work from a number of laboratories, including our own, has demonstrated that cartilage is an enriched source of endogenous inhibitors of angiogenesis. In the course of a study designed to identify novel
Percy J Russell et al.
Journal of enzyme inhibition and medicinal chemistry, 19(1), 91-98 (2004-06-19)
Muscle-type LDH (LDH-m4) activity is critical for efficient anaerobic glycolysis. The results here show that rabbit LDH-M4 is inhibited by concentrations of ascorbate normally found in tissues. Aldolase and muscle G-actin were found to protect and to reverse inhibitions of

문서

Troponin together with tropomyosin, regulate the binding of myosin to actin. Troponin is a trimeric protein composed of Troponin subunits I, C and T. Troponin C binds calcium ions, Troponin T binds to tropomyosin and troponin I binds to actin

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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