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Merck
모든 사진(1)

주요 문서

UC448

Sigma-Aldrich

Paracetamol sulfate potassium salt

solid, ≥97% (HPLC)

동의어(들):

4-Acetamidophenol sulfate ester potassium salt, Acetaminophen sulfate potassium salt, N-(4-Sulfoxyphenyl)acetamide monopotassium salt

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About This Item

실험식(Hill 표기법):
C8H8KNO5S
CAS Number:
Molecular Weight:
269.32
MDL number:
UNSPSC 코드:
12161501
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥97% (HPLC)

양식

solid

색상

white to off-white

mp

163 °C

solubility

H2O: soluble

저장 온도

2-8°C

SMILES string

[K+].CC(=O)Nc1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C8H9NO5S.K/c1-6(10)9-7-2-4-8(5-3-7)14-15(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1

InChI key

AJYPYWFCUWHZMZ-UHFFFAOYSA-M

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Paracetamol is an aminophenol derivative. It functions as an analgesic and antipyretic drug, which has weak inflammatory effect. Paracetamol is used to treat pyrexia and mild to moderate pain. It might inhibit atherosclerosis through its antioxidant activity.

애플리케이션

Paracetamol sulfate potassium salt has been used as a standard for HPLC assays of acetaminophen.

생화학적/생리학적 작용

Phase II metabolite of paracetamol.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

제조 메모

Paracetamol sulfate potassium salt is soluble in water.

기타 정보

Occasionally, it may be necessary to supply as the sodium salt

픽토그램

CorrosionExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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문서 라이브러리 방문

D Bougie et al.
Blood, 97(12), 3846-3850 (2001-06-05)
In patients suspected of having drug-induced immune thrombocytopenia, antibodies reactive with normal platelets in the presence of the suspect drug can sometimes be identified, but negative results are often obtained. One reason for this is that drug metabolites, formed in
Paracetamol: past, present, and future.
Prescott LF
American Journal of Therapeutics, 7(2), 143-147 (2000)
Karel Allegaert et al.
Acta paediatrica (Oslo, Norway : 1992), 94(9), 1273-1279 (2005-11-11)
Major changes in drug clearance and metabolism are observed during infancy, in part based on ontogenic regulation of various metabolic pathways. Since paracetamol provides a good substrate to study UGT (1A6) activity, urinary metabolites of propacetamol were determined in neonates
L S Jensen et al.
Journal of pharmaceutical and biomedical analysis, 34(3), 585-593 (2004-05-07)
A range of analytical methods exist for the determination of paracetamol in biological fluids. However, to understand the fate of paracetamol and the effect of other drugs on its disposition in vivo, the major metabolites require quantification in urine and
Hayati Filik et al.
Chemical & pharmaceutical bulletin, 54(6), 891-896 (2006-06-07)
In the present paper, conventional spectrophotometry in conjunction with cloud point extraction-preconcentration were investigated as alternative methods for paracetamol (PCT) assay in urine samples. Cloud point extraction (CPE) was employed for the preconcentration of p-aminophenol (PAP) prior to spectrophotometric determination

문서

Human epithelial intestinal colonic organoids can be used as an alternative to Caco-2 drug permeability assays for drug screening and compound toxicity testing.

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