추천 제품
product name
Vascular Endothelial Growth Factor 164 from rat, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
생물학적 소스
rat
Quality Level
재조합
expressed in NSO cells
분석
>95% (SDS-PAGE)
형태
lyophilized powder
효능
1.08 ng/mL ED50
분자량
dimer 50 kDa by SDS-PAGE
monomer 25 kDa by SDS-PAGE
포장
pkg of 10 μg
저장 조건
avoid repeated freeze/thaw cycles
불순물
endotoxin, tested
UniProt 수납 번호
저장 온도
−20°C
유전자 정보
rat ... Vegfa(83785)
애플리케이션
Vascular Endothelial Growth Factor 164 (VEGF 164) from rat was used for cardiomyocytes culture and Ca2+ transients′ measurement. It was used as a medium M-199 supplement utilized in in vitro incubation for examining the capability of CTS to limit the impact of biologically relevant molecules, in particular epidermal growth factor (EGF), basic fibroblast growth factor (FGF2), and vascular endothelial growth factor A (VEGFA) in rat epididymis segment 1 and 2.
생화학적/생리학적 작용
Vascular Endothelial Growth Factor 164 also referred to as VEGF 164 or Vasculotropin is a growth factor that induces endothelial cell growth, vasculogenesis and angiogenesis. VEGF 164 can enhance collagen and fibronectin expression in mesangial cells which in turn stimulates TGF-β1-induced extracellular matrix. It also plays a pivotal role in progressive glomerular fibrosis.
Mitogen for endothelial cells, enhances vascular permeability, activates, and chemoattracts monocytes and is a procoagulant.
기타 정보
164 amino acid variant of rat VEGF.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in 35% acetonitrile and 0.1% TFA containing 0.5 mg bovine serum albumin.
분석 메모
The biological activity is measured by its ability to stimulate 3H-thymidine incorporation in human umbilical vein endothelial cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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The Journal of biological chemistry, 279(32), 33213-33219 (2004-05-15)
Transforming growth factor-beta1 (TGF-beta1) is a potent inducer of extracellular matrix synthesis leading to progressive glomerular fibrosis. The intracellular signaling mechanisms involved in this process remain incompletely understood. The p38 mitogen-activated protein kinase (MAPK) is a major stress signal transducing
문서
VEGF-A stimulates blood vessel growth via endothelial cell proliferation, migration, and survival during embryonic development.
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