Z0167

Zearalanone

• 동의어(들): 2,4-Dihydroxy-6-(10-hydroxy-6-oxoundecyl)benzoic acid μ-lactone
• 실험식(Hill 표기법): C₁₈H₂₄O₅
• CAS Number: 5975-78-0
• Molecular Weight: 320.38
• MDL number: MFCD00135821
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24902160
• NACRES: NA.77

속성

• 무균: non-sterile
• Quality Level: 200
• 분석: ≥98% (TLC)
• 형태: powder
• solubility: methanol: 9.80-10.20 mg/mL, clear, colorless
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: C[C@H]1CCCC(=O)CCCCCc2cc(O)cc(O)c2C(=O)O1
• InChI: 1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1
• InChI key: APJDQUGPCJRQRJ-LBPRGKRZSA-N
• 유전자 정보: rat ... Ar(24208)

설명

일반 설명

Zearalanone (ZEA) or F-2 toxin, a nonsteroidal estrogenic mycotoxin is produced by various Fusarium species. Fusarium graminearum is considered as the primary producer of zearalanone. It is usually seen in moldy hay, high-moisture corn, corn infected before harvest etc.

애플리케이션

Zearalanone has been used:

• as mycotoxin to study its effects on the histology of ovaries in pre-pubertal bitches
• as a mycotoxin to investigate its influence on selected immunological, haematological and biochemical indexes in bitches
• as a standard to develop calibration curves in order to study its effects on progesterone and 17β-estradiol concentrations in peripheral blood and body weights of pre-pubertal female Beagle dogs
• as a standard to develop calibration curves to study its level of intoxication in women with neoplastic lesions in the reproductive tract

생화학적/생리학적 작용

Zearalanone is believed to cause vulvovaginitis and estrogenic responses in swine.

안전성 정보

• 픽토그램: GHS08,GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302 + H312 + H332,H315,H319,H335,H351
• 예방조치 성명서: P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges