Z4250

Zymosan A from Saccharomyces cerevisiae

for inducing inflamatory response

• 동의어(들): Yeast Cell Wall
• CAS Number: 58856-93-2
• MDL number: MFCD00082157
• UNSPSC 코드: 12352202
• NACRES: NA.61

속성

• 생물학적 소스: Saccharomyces cerevisiae
• Quality Level: 200
• 양식: powder with small lumps
• 기술: flow cytometry: suitable; tissue culture: suitable
• 색상: off-white to light brown
• 저장 온도: 2-8°C

설명

애플리케이션

• in flow cytometry
• to study its effect on head kidney leukocytes from rainbow trout (Oncorhynchus mykiss)

Zymosan A from Saccharomyces cerevisiae has been used:

• as a positive control to determine the activation of complement cascade
• for respiratory burst (RB) assay
• to assess its effects on performance, immunity, heat shock protein and apoptosis related gene expressions of dairy cows under heat stress (HS)
• a stimulating agent in Krebs-Ringer phosphate (KRP) medium
• to induce thermal hyperalgesia in mice

생화학적/생리학적 작용

Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection suggesting that certain types of nonparenchymal cells other than Kupffer cells are involved in zymosan action. Zymosan A, a 13 beta glucan contributes to the development of organic dust-induced respiratory disease.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)