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Merck
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14023AST

Supelco

Astec® CHIROBIOTIC® TAG Chiral (5 μm) HPLC Columns

L × I.D. 15 cm × 4.6 mm, HPLC Column

동의어(들):

Chirobiotic TAG Chiral Chromatography Column

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About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Astec® CHIROBIOTIC® TAG Chiral HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm

material

stainless steel column

Agency

suitable for USP L63

설명

HPLC column

제품 라인

Astec®

포장

pkg of 1 ea

제조업체/상표

Astec®

파라미터

0-45 °C temperature
241 bar pressure (3500 psi)

기술

HPLC: suitable
LC/MS: suitable

길이 × I.D.

15 cm × 4.6 mm

기질

High-purity silica gel particle platform
fully porous particle

기질 활성군

teicoplanin aglycone phase

입자 크기

5 μm

공극 크기

100 Å

operating pH range

3.0-6.8

분리 기술

chiral

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

The removal of three carbohydrate moieties gives CHIROBIOTIC® TAG complementary selectivity to CHIROBIOTIC® T. Resolution is enhanced toward many of the amino acids, α, β, γ and cyclic, and especially sulfur-containing methionine, histidine and cysteine. A number of neutral molecules like the oxazolidinones, hydantoins and diazepines have shown enhanced resolution and, more remarkably, in the single solvents like methanol, ethanol and acetonitrile. Some acidic molecules have also shown increased selectivity.

  • Bonded phase: Teicoplanin aglycone
  • Operating pH range: 3.0 - 6.8
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å

애플리케이션


  • High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This study emphasizes the effectiveness of the Astec® CHIROBIOTIC® TAG Chiral HPLC Column in the enantioseparation of complex cyclic amino acids. The methodology detailed provides profound insights into the chirality aspects of biochemical molecules, which is crucial for the synthesis of novel pharmaceutical agents and the study of biochemical pathways. This research supports analytical chemists in academia focused on developing chiral analytical methods and advancing chemical synthesis (Berkecz et al., 2009).


추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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문서 라이브러리 방문

Markus Fuereder et al.
Journal of chromatography. A, 1236, 123-131 (2012-04-03)
Teicoplanin aglycone-based chromatography columns (Chirobiotic TAG) enable amino acid enantioseparation with aqueous mobile phases, which perfectly accommodates the distinct hydrophilicity of most amino acids. Therefore, this stationary phase constitutes a promising option in particular for preparative-scale separations that require high
Abdulrahman A Al-Majed
Journal of pharmaceutical and biomedical analysis, 50(1), 96-99 (2009-05-19)
A direct chiral high-performance liquid chromatography (HPLC) method was developed and validated for the resolution and quantification of antiepileptic drug enantiomers, R-(-)- and S-(+)-vigabatrin (gamma-vinyl-gamma-aminobutyric acid) in pharmaceutical products. The separation was optimized on a macrocyclic glycopeptide antibiotic chiral stationary
Ilaria D'Acquarica et al.
Journal of chromatography. A, 1061(2), 167-173 (2005-01-12)
We describe a new tandem-columns chiral-achiral HPLC arrangement by using a chiral column (CHIROBIOTIC TAG) connected in series with an achiral column (Spherisorb S5 SCX), based on a strong cationic exchange mechanism; this approach is very useful for the analysis
Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions
Bechtold, Matthias, et al.
Journal of Chromatography A, 1154 (1-2), 2477-2286 (2007)
Chemoenzymatic preparation of enantiopure l-benzofuranyl- and l-benzo[b]thiophenyl alanines
Podea, Paula Veronica, et al.
Tetrahedron Asymmetry, 19 (4), 500-511 (2008)

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