추천 제품
Grade
analytical standard
Quality Level
CofA
current certificate can be downloaded
포장
ampule of 50 mg
기술
HPLC: suitable
gas chromatography (GC): suitable
bp
280 °C/80 mmHg (lit.)
mp
178-180 °C (lit.)
응용 분야
environmental
형식
neat
저장 온도
2-30°C
SMILES string
Cc1ccc2cc3c(ccc4ccccc34)c5CCc1c25
InChI
1S/C21H16/c1-13-6-7-15-12-20-17-5-3-2-4-14(17)8-9-18(20)19-11-10-16(13)21(15)19/h2-9,12H,10-11H2,1H3
InChI key
PPQNQXQZIWHJRB-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
3-Methylcholanthrene, a potent polycyclic aryl hydrocarbon receptor agonist, which is a carcinogen that can be obtained as a byproduct of combustion of various organic substances like coal, garbage, gas and oil. It suppresses the proliferation of human umbilical vascular endothelial cells.
애플리케이션
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Aquatic Chronic 4 - Carc. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Attenuation of polycyclic aromatic hydrocarbon (PAH)-mediated pulmonary carcinogenesis in mice by omega-3-fatty acids
Faseb Journal, 31, 1067-1064 (2017)
Mechanism of p53-dependent apoptosis induced by 3-methylcholanthrene involvement of p53 phosphorylation and p38 MAPK
The Journal of Biological Chemistry, 277, 1837-1844 (2002)
Molecular mechanisms of p21 and p27 induction by 3?methylcholanthrene, an aryl?hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells
Journal of Cellular Physiology, 215, 161-171 (2008)
3?Methylcholanthrene/Aryl?Hydrocarbon Receptor?Mediated Hypertension Through eNOS Inactivation
Journal of Cellular Physiology, 232, 1020-1029 (2017)
Molecular and cellular endocrinology, 362(1-2), 39-47 (2012-05-29)
The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (EDCs), compounds that interfere with hormonal signaling. 3-Methylcholanthrene (3-MC) and dioxin (TCDD) are EDCs and prototypical aryl hydrocarbon receptor
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