추천 제품
Grade
analytical standard
Quality Level
CofA
current certificate can be downloaded
특징
standard type water soluble vitamin
포장
ampule of 1000 mg
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
236-239 °C (lit.)
density
1.473 g/cm3 at 25 °C
응용 분야
pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products
형식
neat
저장 온도
2-30°C
SMILES string
OC(=O)c1cccnc1
InChI
1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI key
PVNIIMVLHYAWGP-UHFFFAOYSA-N
유전자 정보
human ... CYP1A2(1544)
rat ... Chrnb2(54239)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Nicotinic acid acts as an antilipolytic drug in adipose tissue, and is commonly used for hyperlipoproteinaemia and pellagra.
Nicotinic acid is a water soluble, vitamin belonging to B complex group of vitamins, which can be used as a broad spectrum lipid lowering drug. Its mode of action basically involves the inhibition of the hormone-sensitive triglyceride lipase and thereby, decreasing the lipolysis in adipose tissue.
애플리케이션
Nicotinic acid may be used as an analytical reference standard for the quantification of the analyte in tablet dosage forms using reversed-phase high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
379.4 °F - closed cup
Flash Point (°C)
193 °C - closed cup
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Nicotinic acid: the broad?spectrum lipid drug. A 50th anniversary review
J. Int. Med., 258, 94-114 (2005)
Molecular identification of nicotinic acid receptor
Biochemical and Biophysical Research Communications, 303, 364-369 (2003)
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect
Nature Medicine, 9, 352-352 (2003)
RP-HPLC method for the determination of atorvastatin calcium and nicotinic acid in combined tablet dosage form
Indian Journal of Pharmaceutical Sciences, 69(5), 700-700 (2007)
Stroke, 44(10), 2688-2693 (2013-07-25)
In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental
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