추천 제품
Grade
analytical standard
Quality Level
CofA
current certificate can be downloaded
특징
standard type water soluble vitamin
포장
ampule of 1000 mg
기술
HPLC: suitable
gas chromatography (GC): suitable
mp
128-131 °C (lit.)
응용 분야
clinical testing
형식
neat
저장 온도
2-30°C
SMILES string
NC(=O)c1cccnc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
유전자 정보
human ... PARP1(142) , SIRT2(22933)
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일반 설명
Nicotinamide (Niacinamide), belonging to the class of water-soluble B vitamins, is typically produced from nicotinic acid (vitamin B3). It is found as a component of food products. It has been suggested for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It also exhibits anti-inflammatory activity.
애플리케이션
Nicotinamide (Niacinamide) may be used as a reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
생화학적/생리학적 작용
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
추천 제품
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
302.0 °F - closed cup
Flash Point (°C)
150 °C - closed cup
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
Industrial application of green chromatography?I. Separation and analysis of niacinamide in skincare creams using pure water as the mobile phase
Talanta, 84(1), 169-174 (2011)
Evaluation of analytical tools and multivariate methods for quantification of co-former crystals in ibuprofen-nicotinamide co-crystals
Journal of Pharmaceutical and Biomedical Analysis, 89, 166-175 (2014)
Nicotinamide
European pharmacopoeia, 14(4), 3145-3146 (2017)
Journal of the American Chemical Society, 141(22), 8951-8968 (2019-05-08)
Covalent probes can display unmatched potency, selectivity, and duration of action; however, their discovery is challenging. In principle, fragments that can irreversibly bind their target can overcome the low affinity that limits reversible fragment screening, but such electrophilic fragments were
Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceuticals and biological fluids after solid phase extraction
Journal of Separation Science, 27(14), 1181-1188 (2004)
문서
Learn to separate and quantify B vitamins and preservatives in capsules with HPLC-UV and Purospher® STAR RP-8 column. Validated for precision.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.