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Merck
모든 사진(2)

문서

504955-30

Supelco

Discovery® C18 (5 µm) HPLC Columns

L × I.D. 15 cm × 3 mm, HPLC Column

동의어(들):

C18 TM=["Discovery"] HPLC Column

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About This Item

UNSPSC 코드:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® C18 HPLC Column, 5 μm particle size, L × I.D. 15 cm × 3 mm

material

stainless steel column

Agency

suitable for USP L1

제품 라인

Discovery®

특징

endcapped

제조업체/상표

Discovery®

포장

1 ea of

라벨링 범위

12% Carbon loading

파라미터

≤70 °C temp. range
400 bar pressure (5801 psi)

기술

HPLC: suitable
LC/MS: suitable

길이 × I.D.

15 cm × 3 mm

표면적

300 m2/g

표면 범위

3 μmol/m2

불순물

<10 ppm metals

기질

silica gel, high purity, spherical particle platform
fully porous particle

기질 활성군

C18 (octadecyl) phase

입자 크기

5 μm

공극 크기

180 Å

operating pH range

2-8

응용 분야

food and beverages

분리 기술

reversed phase

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일반 설명

Use Discovery® C18 for any method that specifies a C18. The exceptional peak shape, reproducibility, and stability make it the column of choice for all C18 methods from demanding to routine.

애플리케이션


  • A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This paper describes the use of the Discovery® C18 HPLC Column in developing a stability-indicating method for the COVID-19 therapeutic, molnupiravir, emphasizing its critical role in supporting pandemic response through advanced drug formulation and analysis (Recber et al., 2022).

  • Features of assay and decomposition dynamics of 2-methoxy-4-(1-propenyl)hydroxybenzene in biological material.: Demonstrates the versatility of the Discovery® C18 HPLC Column in forensic science, particularly in the analysis and decomposition studies of complex organic compounds within biological samples (Chernova et al., 2022).

특징 및 장점

  • Excellent reproducibility
  • Exceptional peak shape for basic and acidic analytes
  • Stable, low-bleed LC-MS separations
  • Separation of peptides and small proteins
  • Lower hydrophobicity than many comparable C18 columns, providing faster analysis

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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시험 성적서(COA)

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문서 라이브러리 방문

Yoshinori Masukawa et al.
Journal of lipid research, 49(7), 1466-1476 (2008-03-25)
Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species might be closely related to the regulation of keratinization, together with other CER-related lipids. Structures of those diverse
Pei Yuan et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 15(42), 11319-11325 (2009-09-18)
This study systematically investigates periodic mesoporous organosilicas (PMOs) with controlled helical and concentric circular (CC) pore architectures prepared through a basic-catalyzed sol-gel process by using an achiral cationic surfactant trimethyloctadecylammonium bromide (C(18)TAB) as a structure-directing agent, perfluorooctanoic acid (PFOA) as
R Nageswara Rao et al.
Biomedical chromatography : BMC, 23(11), 1145-1150 (2009-05-16)
A highly sensitive and selective on-line two-dimensional reversed-phase liquid chromatography/electrospray ionization-tandem mass spectrometry (2D-LC-ESI/MS/MS) method was developed and validated to determine rifaximin in rat serum by direct injection. The 2D-LC-ESI/MS/MS system consisted of a restricted access media column for trapping
Pilar Heredia-Middleton et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 149(4), 552-556 (2008-02-01)
Heat shock protein 70 (HSP70, 70 kDa) is the most commonly expressed protein in response to thermal stress. The extent of its expression is associated with differences in environmental temperatures. We investigated the heat shock response in red blood cells
Xiaofang Hou et al.
Journal of separation science, 36(4), 706-712 (2013-02-13)
Most of the anti-breast cancer drugs are often limited owing to drug resistance and serious adverse reactions. Therefore, development of more targeted and low toxic drugs from traditional Chinese medicines for breast cancer are needed. At the same time, establishment

관련 콘텐츠

Discovery C18 and C8 HPLC Columns products offered

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