569232-U

Discovery^® C18 (5 µm) HPLC Columns

L × I.D. 12.5 cm × 4.6 mm, HPLC Column

• 동의어(들): Discovery RP18 HPLC Column
• UNSPSC 코드: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

속성

• product name: Discovery^® C18 HPLC Column, 5 μm particle size, L × I.D. 12.5 cm × 4.6 mm
• material: stainless steel column
• Quality Level: 100
• Agency: suitable for USP L1
• 제품 라인: Discovery^®
• 특징: endcapped
• 제조업체/상표: Discovery^®
• 포장: 1 ea of
• 라벨링 범위: 12% Carbon loading
• 파라미터: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• 기술: HPLC: suitable; LC/MS: suitable
• 길이 × I.D.: 12.5 cm × 4.6 mm
• 표면적: 300 m²/g
• 표면 범위: 3 μmol/m²
• 불순물: <10 ppm metals
• 기질: silica gel, high purity, spherical particle platform; fully porous particle
• 기질 활성군: C18 (octadecyl) phase
• 입자 크기: 5 μm
• 공극 크기: 180 Å
• operating pH range: 2-8
• 응용 분야: food and beverages
• 분리 기술: reversed phase

설명

일반 설명

Use Discovery® C18 for any method that specifies a C18. The exceptional peak shape, reproducibility, and stability make it the column of choice for all C18 methods from demanding to routine.

애플리케이션

• Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson′s Disease Candidate, Using LC-MS/MS and LC-HRMS.: This study underscores the utility of theDiscovery^® C18 HPLC Column in pharmacokinetic profiling and metabolite identification of a novel therapeutic agent, demonstrating its critical role in the development of Parkinson′s disease treatments (Choi et al., 2024).


• Determination of 2,4-dimethylhydroxybenzene by chromatographic methods in forensic toxicological research of biological material.: Highlights the application of the Discovery^® C18 HPLC Column in forensic toxicology, enhancing the detection and quantification of toxic substances within biological samples, vital for legal and medical investigations (Chernova et al., 2024).


• High-throughput microfluidic chip with silica gel-C18 channels for cyclotide separation.: Illustrates the integration of the Discovery^® C18 HPLC Column in a microfluidic setting for efficient and high-throughput separation of cyclotides, offering advancements in peptide and protein analysis (Ebrahimi et al., 2023).


• Priestia megaterium Metabolism: Isolation, Identification of Naringenin Analogues and Genes Elevated Associated with Nanoparticle Intervention.: This research utilizes the Discovery^® C18 HPLC Column for the advanced study of microbial metabolism under nanoparticle intervention, pushing the boundaries of biotechnological and pharmaceutical research (Al-Theyab et al., 2023).


• A practical strategy enabling more reliable identification of ginsenosides from Panax quinquefolius flower by dimension-enhanced liquid chromatography/mass spectrometry and quantitative structure-retention relationship-based retention behavior prediction.: Demonstrates the versatility of the Discovery^® C18 HPLC Column in complex botanical analyses, particularly in enhancing the reliability of ginsenoside identification, crucial for the development of herbal medicinal products (Sun et al., 2023).

특징 및 장점

• Excellent reproducibility
• Exceptional peak shape for basic and acidic analytes
• Stable, low-bleed LC-MS separations
• Separation of peptides and small proteins
• Lower hydrophobicity than many comparable C18 columns, providing faster analysis

추천 제품

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

법적 정보

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany