PHL89159

Apigenin

phyproof^® Reference Substance

• 동의어(들): 4′,5,7-Trihydroxyflavone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
• 실험식(Hill 표기법): C₁₅H₁₀O₅
• CAS Number: 520-36-5
• Molecular Weight: 270.24
• Beilstein: 262620
• MDL number: MFCD00006831
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: primary reference standard
• 제품 라인: phyproof^® Reference Substance
• 분석: ≥95.0% (HPLC)
• 형태: powder
• 제조업체/상표: PhytoLab
• mp: >300 °C (lit.)
• SMILES string: Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
• InChI key: KZNIFHPLKGYRTM-UHFFFAOYSA-N

설명

일반 설명

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

생화학적/생리학적 작용

A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G₂/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

기타 정보

This compound is commonly found in plants of the genus: achillea mentha pimpinella primula salvia silybum thymus

법적 정보

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3