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Merck
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주요 문서

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1133547

USP

Choline chloride

United States Pharmacopeia (USP) Reference Standard

동의어(들):

(2-Hydroxyethyl)trimethylammonium chloride

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About This Item

Linear Formula:
(CH3)3N(Cl)CH2CH2OH
CAS Number:
67-48-1
Molecular Weight:
139.62
Beilstein:
3563126
MDL number:
MFCD00011721
UNSPSC 코드:
41116107
PubChem Substance ID:
329749389
NACRES:
NA.24

Grade

pharmaceutical primary standard

제조업체/상표

USP

mp

302-305 °C (dec.) (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

[Cl-].C[N+](C)(C)CCO

InChI

1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1

InChI key

SGMZJAMFUVOLNK-UHFFFAOYSA-M

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션



  • Extraction of Bioactive Compounds: Choline chloride, combined with sucrose in natural deep eutectic solvents, facilitates the formation of aqueous biphasic systems. These systems are applied in drug extraction processes to improve efficiency and selectivity, particularly in pharmaceutical applications (Ghaffari et al., 2024).


  • Extraction of α-Glucosidase Inhibitors: Utilizing choline chloride-based deep eutectic solvents significantly enhances the selective extraction of α-glucosidase inhibitors from waste seeds. This application is particularly valuable in the development of therapeutic agents for diabetes management, showcasing its versatility in pharmaceutical extraction processes (Liu et al., 2024).


기질

Choline acetyltransferase substrate

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

USP issued SDS can be found here.
Sales restrictions may apply.

관련 제품

제품 번호
설명
가격

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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문서 라이브러리 방문

Xinyin Jiang et al.
Journal of cellular physiology, 229(8), 1016-1027 (2014-03-22)
Maternal choline intake during gestation may influence placental function and fetal health outcomes. Specifically, we previously showed that supplemental choline reduced placental and maternal circulating concentrations of the anti-angiogenic factor, fms-like tyrosine kinase-1 (sFLT1), in pregnant women as well as
Zhuo Li et al.
Biochimica et biophysica acta, 1840(7), 2112-2122 (2014-03-19)
Choline kinase has three isoforms encoded by the genes Chka and Chkb. Inactivation of Chka in mice results in embryonic lethality, whereas Chkb(-/-) mice display neonatal forelimb bone deformations. To understand the mechanisms underlying the bone deformations, we compared the
Francina Agosti et al.
The European journal of neuroscience, 40(5), 2755-2765 (2014-06-20)
The melanocortin 4 receptor (MC4R) is a G protein-coupled receptor involved in food intake and energy expenditure regulation. MC4R activation modifies neuronal activity but the molecular mechanisms by which this regulation occurs remain unclear. Here, we tested the hypothesis that
O Hemminki et al.
International journal of cancer, 134(12), 2878-2890 (2013-11-20)
At present, it is not possible to reliably identify patients who will benefit from oncolytic virus treatments. Conventional modalities such as computed tomography (CT), which measure tumor size, are unreliable owing to inflammation-induced tumor swelling. We hypothesized that magnetic resonance
Brook T Chernet et al.
Oncotarget, 5(10), 3287-3306 (2014-05-17)
The microenvironment is increasingly recognized as a crucial aspect of cancer. In contrast and complement to the field's focus on biochemical factors and extracellular matrix, we characterize a novel aspect of host:tumor interaction - endogenous bioelectric signals among non-excitable somatic
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