MilliporeSigma

CNR2

cannabinoid receptor 2 (macrophage)

Synonyms:
CB-2, CB2, CX5
Species:
UniProtKB ID:
Gene ID:
  • Human(1269) Summary: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
  • Mouse(12802) cannabinoid receptor 2 (macrophage)
  • Rat(57302) cannabinoid receptor 2 (macrophage)
  • chicken(428232) cannabinoid receptor 2 (macrophage)
  • Horse(100071536) cannabinoid receptor 2 (macrophage)
  • domestic cat(101100234) cannabinoid receptor 2 (macrophage)
  • dog(612289) cannabinoid receptor 2 (macrophage)
  • cow(539769) cannabinoid receptor 2 (macrophage)
  • sheep(101119188) cannabinoid receptor 2 (macrophage)
  • domestic guinea pig(100721528) cannabinoid receptor 2 (macrophage)
  • Zebrafish(795246) cannabinoid receptor 2

Custom & Knockdown Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
(R)-(+)-WIN 55,212-2 mesylate salt, ≥98% (HPLC),
Species
human
Arachidonyl-2′-chloroethylamide hydrate, ≥97% (HPLC), oil,
Species
rat, mouse
Δ9-Tetrahydrocannabinol solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis,
Species
human, mouse, rat
Δ9-Tetrahydrocannabinol solution, ethanol solution,
Species
human, mouse, rat
L-Thyroxine, powder, BioReagent, suitable for cell culture,
Species
human, mouse, rat

Small Molecule - Antagonist

Product Number
Description
Species
L-Thyroxine sodium salt pentahydrate, ≥98% (HPLC), powder,
Species
mouse, rat
L-Thyroxine sodium salt pentahydrate, γ-irradiated, powder, BioXtra, suitable for cell culture,
Species
mouse, rat
JWH-015, ≥98% (HPLC), powder,
Species
rat, human
Palmitoylethanolamide, ,
Species
human, rat
2-Arachidonyl glycerol, ~10 mg/mL, ≥98% (HPLC),
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CNR2 antibody produced in mouse, clone 3C7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-CNR2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
Anti-Cannabinoid Receptor 2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, rat
Application
immunocytochemistry
western blot

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
JWH-015, ≥98% (HPLC), powder,
Species
rat, human
Palmitoylethanolamide, ,
Species
human, rat
CP-55940, >98% (HPLC), powder,
Species
human, rat
Δ9-Tetrahydrocannabinol solution, 1.0 mg/mL in methanol, analytical standard, for drug analysis,
Species
human, mouse, rat
Δ9-Tetrahydrocannabinol solution, ethanol solution,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CNR2,
Species
human