MilliporeSigma

COL1A2

collagen, type I, alpha 2

Synonyms:
OI4
Species:
UniProtKB ID:
Gene ID:
  • Human(1278) Summary: This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
  • Mouse(12843) collagen, type I, alpha 2
  • Rat(84352) collagen, type I, alpha 2
  • chicken(396243) collagen, type I, alpha 2
  • domestic guinea pig(100719158) collagen, type I, alpha 2
  • domestic cat(101089428) collagen, type I, alpha 2
  • Horse(100051715) collagen, type I, alpha 2
  • Zebrafish(336471) collagen, type I, alpha 2
  • Domestic Rabbit(100008997) collagen, type I, alpha 2
  • dog(403824) collagen, type I, alpha 2
  • naked mole-rat(101722393) collagen, type I, alpha 2
  • cow(282188) collagen, type I, alpha 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Collagen I α2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Collagen I antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry
Anti-COL1A2 antibody produced in rabbit, ,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Anti-COL1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

Proteins

Product Number
Description
Species
Collagen from rabbit skin, Bornstein and Traub Type I, powder,
Species
domestic rabbit
Collagen human, Bornstein and Traub Type I, acid soluble, powder, ~95% (SDS-PAGE),
Species
human
Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution,
Species
cow, rat, human, mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human COL1A2,
Species
human