MilliporeSigma

TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

Synonyms:
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
Species:
UniProtKB ID:
Gene ID:
  • Human(7048) Summary: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(21813) transforming growth factor, beta receptor II
  • Rat(81810) transforming growth factor, beta receptor II
  • Horse(100033860) transforming growth factor, beta receptor II (70/80kDa)
  • Zebrafish(30739) transforming growth factor, beta receptor II
  • chicken(396399) transforming growth factor, beta receptor II (70/80kDa)
  • domestic guinea pig(100718284) transforming growth factor, beta receptor II (70/80kDa)
  • dog(477039) transforming growth factor, beta receptor II (70/80kDa)
  • domestic cat(101091725) transforming growth factor, beta receptor II (70/80kDa)
  • cow(535376) transforming growth factor, beta receptor II (70/80kDa)
  • sheep(494191) transforming growth factor, beta receptor II (70/80kDa)
  • naked mole-rat(101704397) transforming growth factor, beta receptor II (70/80kDa)

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ELISA

Product Number
Description
Species
Human TGFBR2 / TGF-beta Receptor Type-2 ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TGFBR2 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, rabbit
Application
western blot
Anti-phospho-TGF β Receptor II (pSer225/250) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
Anti-TGFBR2 Antibody, clone 1N11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-TGFBR2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-TGF beta Receptor II (TGFBR2) Antibody, clone 2M8Y2, Rabbit Monoclonal, ,
Species Reactivity
human
Application
western blot

Proteins

Product Number
Description
Species
TGFβR2 (190-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Transforming Growth Factor-β2 human, TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Tgfbr2,
Species
mouse