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UBB

ubiquitin B

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(7314) Summary: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(22187) ubiquitin B
  • Rat(192255) ubiquitin B
  • Zebrafish(550134) ubiquitin B
  • chicken(396190) ubiquitin B
  • dog(479513) ubiquitin B
  • domestic cat(101091319) ubiquitin B
  • Horse(100049794) ubiquitin B
  • cow(281370) ubiquitin B
  • naked mole-rat(101702552) ubiquitin B
  • domestic guinea pig(100722422) ubiquitin B

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Ubiquitin Antibody, clone 5Y8J0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
Anti-Ubiquitin Rabbit pAb, liquid, Calbiochem®,
Species Reactivity
drosophila, e. coli, bovine, canine, chicken, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, sheep, yeast
Application
Anti-UBB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-Ubiquitin (pan) Antibody, clone 2G7B8, clone 2G7B8, from mouse,
Species Reactivity
human
Application
western blot
Milli-Mark® Anti-Ubiquitin Antibody, Lys63-Specific-Alexa Fluor647, clone Apu3, clone Apu3, Milli-Mark®, from rabbit,
Species Reactivity
human
Application
flow cytometry

Proteins

Product Number
Description
Species
Ubiquitin human, recombinant, expressed in E. coli (N-terminal histidine tagged),
Species
human
Ubiquitin human, ≥95% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal FLAG® tagged), lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ubb,
Species
mouse
MISSION® esiRNA, targeting human UBB,
Species
human