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112720

Sigma-Aldrich

N,N-Diethylethylenediamine

≥99%

Synonym(s):

2-Diethylaminoethylamine

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About This Item

Linear Formula:
(C2H5)2NCH2CH2NH2
CAS Number:
100-36-7
Molecular Weight:
116.20
Beilstein/REAXYS Number:
605299
EC Number:
202-844-7
MDL number:
MFCD00008176
UNSPSC Code:
12352100
PubChem Substance ID:
24847111
NACRES:
NA.22

assay

≥99%

refractive index

n20/D 1.436 (lit.)

bp

145-147 °C (lit.)

density

0.827 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

CCN(CC)CCN

InChI

1S/C6H16N2/c1-3-8(4-2)6-5-7/h3-7H2,1-2H3

InChI key

UDGSVBYJWHOHNN-UHFFFAOYSA-N

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Application

N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides.
N,N-diethylethylenediamine was used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Flam. Liq. 3 - Skin Corr. 1A

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

89.6 °F - closed cup

flash_point_c

32 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB0704
STBL1831
STBK7442
STBK2601
STBK0001

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J M Dagle et al.
Nucleic acids research, 28(10), 2153-2157 (2000-04-25)
We have designed a new class of modified antisense oligodeoxyribonucleotides (ODN) consisting of a central contiguous stretch of 6-8 unmodified nucleotides flanked by 3'- and 5'-regions containing several nucleotides joined by cationic internucleoside linkages. The positive charge results from modification
Hongguang Liu et al.
Molecular pharmaceutics, 10(9), 3384-3391 (2013-08-10)
Radiofluorinated benzamide and nicotinamide analogues are promising molecular probes for the positron emission tomography (PET) imaging of melanoma. Compounds containing aromatic (benzene or pyridine) and N,N-diethylethylenediamine groups have been successfully used for development of melanin targeted PET and single-photon emission
Diana Salakhieva et al.
International journal of pharmaceutics, 517(1-2), 234-246 (2016-12-10)
A series of 14 cationic derivatives of poly(aspartic acid) i.e. cationic polyaspartamides with different (dialkylamino)alkyl and alkyl or hydroxyalkyl side groups was synthesized by nucleophilic addition on polysuccinimide. The resulting polyaspartamides have moderate amphiphilic properties. Relationships between the structure and
Vincenzo Taresco et al.
Materials science & engineering. C, Materials for biological applications, 52, 72-81 (2015-05-09)
The application of magnetic nanoparticles (MNPs) in medicine is considered much promising especially because they can be handled and directed to specific body sites by external magnetic fields. MNPs have been investigated in magnetic resonance imaging, hyperthermia and drug targeting.
Feng-Yun J Huang et al.
International journal of nanomedicine, 10, 463-473 (2015-01-28)
In this study, the (188)Re-labeled PEGylated nanoliposome ((188)Re-liposome) was prepared and evaluated as a therapeutic agent for glioma. The reporter cell line, F98(luc) was prepared via Lentivector expression kit system and used to set up the orthotopic glioma-bearing rat model
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