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114480

Sigma-Aldrich

Cresol Red sodium salt

indicator grade

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About This Item

Empirical Formula (Hill Notation):
C21H17NaO5S
CAS Number:
62625-29-0
Molecular Weight:
404.41
EC Number:
263-654-8
MDL number:
MFCD00001618
UNSPSC Code:
12171500
PubChem Substance ID:
24847175
NACRES:
NA.47

grade

indicator grade

form

solid

mp

250 °C (dec.) (lit.)

solubility

H2O: 1 mg/mL

λmax

425 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].Cc1cc(ccc1O)\C(=C2/C=CC(=O)C(C)=C2)c3ccccc3S([O-])(=O)=O

InChI

1S/C21H18O5S.Na/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26;/h3-12,22H,1-2H3,(H,24,25,26);/q;+1/p-1/b21-16-;

InChI key

GBXGEGUVARLBPB-PLMZOXRSSA-M

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Application

Cresol Red has been used for checking the immobilized carbonic anhydrase-catalyzed reactions. It has also been used in the loading buffer for MHC (major histocompatibility complex) class I typing through PCR.

Biochem/physiol Actions

Cresol Red is used as a pH indicator.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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K Horie et al.
Analytical biochemistry, 137(1), 80-87 (1984-02-01)
A highly sensitive quantitative method was developed to detect protons released or taken up upon ligand binding. A small change in pH due to proton release or uptake was detected by measuring the difference in the absorbance of a pH
[Fundamental studies on the measurement of urinary NAG and determination of the normal values for NAG activity in various age groups].
Y Iimura et al.
Rinsho byori. The Japanese journal of clinical pathology, 31(2), 179-184 (1983-02-01)
E Hodges et al.
Molecular pathology : MP, 50(3), 164-166 (1997-06-01)
Diagnostic immunoglobulin (Ig) polymerase chain reaction (PCR) clonality analyses need to be simple, reproducible, and rapid. Sucrose and cresol red (gel loading buffer reagents) were added to a routine IgH PCR reaction mix to obviate the need for adding gel
Paula C A Jerónimo et al.
The Analyst, 130(8), 1190-1197 (2005-07-16)
An optical biosensor based on immobilised carbonic anhydrase and its application to the determination of the anti-glaucoma agent acetazolamide by enzyme inhibition measurements, is described. The enzyme and a pH indicator dye, cresol red, were physically immobilised in overlapped sol-gel
K Elamrani et al.
Biochimica et biophysica acta, 727(1), 22-30 (1983-01-05)
The kinetics of H+/OH- diffusion across dimyristoyl phosphatidic acid bilayer membranes was measured by following the absorbance of the pH-sensitive indicator Cresol red (o-cresolsulfonphthalein) entrapped in single lamellar vesicles after rapidly changing the external pH in a stopped-flow apparatus. The
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