11628
Azodicarboxylic dimorpholide
≥98.0% (N)
Synonym(s):
Azodicarboxylic bismorpholide
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About This Item
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Quality Level
assay
≥98.0% (N)
form
solid
mp
141-143 °C
functional group
azo
ether
SMILES string
O=C(\N=N\C(=O)N1CCOCC1)N2CCOCC2
InChI
1S/C10H16N4O4/c15-9(13-1-5-17-6-2-13)11-12-10(16)14-3-7-18-8-4-14/h1-8H2/b12-11+
InChI key
CHAMTJKQPOMXTI-VAWYXSNFSA-N
General description
Azodicarboxylic dimorpholide is a yellow to dark yellow powder or crystals
Application
Azodicarboxylic dimorpholide has been used in the galanthamine ring system reaction that utilizes an intramolecular Heck reaction to establish the benzofuran ring system. Galanthamine exhibits potent acetylcholinesterase inhibitory activity and is important in the management of Alzheimer′s disease.
Other Notes
Reagent for the formation of symmetric and unsymmetric disulfides in polar solvents (e.g. water)
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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A general approach to the galanthamine ring system.
Tetrahedron Letters, 42(11), 2209- 2211 (2001)
Hoppe-Seyler'S Zeitschrift fur Physiologische Chemie, 370, 365 -365 (1989)
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