12072
Benzamidine
≥95.0%
Synonym(s):
Benzenylamidine, Phenylamidine
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About This Item
Linear Formula:
C6H5C(=NH)NH2
CAS Number:
Molecular Weight:
120.15
Beilstein/REAXYS Number:
606020
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
assay
≥95.0%
form
powder or crystals
functional group
amine
phenyl
SMILES string
NC(=N)c1ccccc1
InChI
1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)
InChI key
PXXJHWLDUBFPOL-UHFFFAOYSA-N
Gene Information
human ... F10(2159) , F2(2147) , PLAT(5327) , PLAU(5328) , PLG(5340) , PRSS1(5644)
Related Categories
Application
Benzamidine was used in the preparation of heparan sulfate-rich proteoglycan from mouse mammary epithelial cells. It has been used to prevent enzymatic degradation during the purification procedure of bovine factor XII (Hageman factor).
Biochem/physiol Actions
Benzamidine is an inhibitor of plasmin and has been used in the radioimmunoassay of glucagon in human plasma. It prevents the destruction of Thyrotropin-releasing hormone (TRH) added to whole blood in vitro before radioimmunoassay of TRH.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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European journal of biochemistry, 87(1), 69-74 (1978-06-01)
Use of benzamidine as a proteolytic inhibitor in the radioimmunoassay of glucagon in plasma.
J W Ensinck et al.
The Journal of clinical endocrinology and metabolism, 35(3), 463-467 (1972-09-01)
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The Journal of cell biology, 101(3), 976-984 (1985-09-01)
Mouse mammary epithelial cells, of the normal murine mammary gland (NMuMG) cell line, bear a heparan sulfate-rich proteoglycan (HSPG) on their surfaces. A hybridoma (281-2) secreting a monoclonal antibody that recognizes this HSPG was produced by fusion of SP-2/0 myeloma
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