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143049

Sigma-Aldrich

Aldrithiol-2

98%

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Synonym(s):
2,2′-Dithiodipyridine, 2,2′-Dipyridyl disulfide
Empirical Formula (Hill Notation):
C10H8N2S2
CAS Number:
Molecular Weight:
220.31
Beilstein/REAXYS Number:
154629
EC Number:
MDL number:
PubChem Substance ID:

assay

98%

form

solid

mp

56-58 °C (lit.)

solubility

methanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow

storage temp.

2-8°C

SMILES string

S(Sc1ccccn1)c2ccccn2

InChI

1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

InChI key

HAXFWIACAGNFHA-UHFFFAOYSA-N

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1 of 4

This Item
143057D216305SML3593
vibrant-m

143049

Aldrithiol-2

vibrant-m

143057

Aldrithiol-4

vibrant-m

D216305

2,2′-Bipyridyl

vibrant-m

SML3593

Hexachlorophene

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

solubility

methanol: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow

solubility

95% ethanol: soluble 5%, clear, colorless to light yellow

solubility

ethanol: 100 mg/mL, clear, colorless to faintly yellow

solubility

DMSO: 2 mg/mL, clear

mp

56-58 °C (lit.)

mp

76-78 °C (lit.)

mp

70-73 °C (lit.)

mp

-

form

solid

form

solid

form

powder or crystals, powder or granules

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

General description

Aldrithiol-2 is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.

Application

Aldrithiol-2 was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.
Thiol reagent. Employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.

Legal Information

Aldrithiol is a trademark of Sigma-Aldrich Co. LLC

Pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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