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152803

Sigma-Aldrich

2,4-Dichlorophenylhydrazine hydrochloride

98%

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About This Item

Linear Formula:
Cl2C6H3NHNH2·HCl
CAS Number:
5446-18-4
Molecular Weight:
213.49
Beilstein/REAXYS Number:
3708828
EC Number:
226-659-6
MDL number:
MFCD00012929
UNSPSC Code:
12352100
PubChem Substance ID:
24849261
NACRES:
NA.22

Quality Level

100

assay

98%

mp

220-224 °C (lit.)

SMILES string

Cl.NNc1ccc(Cl)cc1Cl

InChI

1S/C6H6Cl2N2.ClH/c7-4-1-2-6(10-9)5(8)3-4;/h1-3,10H,9H2;1H

InChI key

DDWYGJVFURAIJZ-UHFFFAOYSA-N

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Application

2,4-Dichlorophenylhydrazine hydrochloride was used in the synthesis of pyrazole analogues of curcumin.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Satyendra Mishra et al.
Bioorganic & medicinal chemistry, 16(6), 2894-2902 (2008-01-16)
Curcumin, a major yellow pigment and active component of turmeric, has been shown to possess anti-inflammatory and anti-cancer activities. Recent studies have indicated that curcumin inhibits chloroquine-sensitive (CQ-S) and chloroquine-resistant (CQ-R) Plasmodium falciparum growth in culture with an IC(50) of

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