156159

Sodium cyanoborohydride

reagent grade, 95%

• Synonym(s): Sodium cyanotrihydridoborate
• Linear Formula: NaBH₃CN
• CAS Number: 25895-60-7
• Molecular Weight: 62.84
• Beilstein/REAXYS Number: 4152656
• EC Number: 247-317-2
• MDL number: MFCD00003516
• UNSPSC Code: 12352306
• PubChem Substance ID: 24849595
• NACRES: NA.22

Properties

• grade: reagent grade
• Quality Level: 300
• assay: 95%
• form: powder
• reaction suitability: reagent type: reductant
• mp: >242 °C (dec.) (lit.)
• SMILES string: [Na+].[BH3-]C#N
• InChI: 1S/CH3BN.Na/c2-1-3;/h2H3;/q-1;+1
• InChI key: CVDUGUOQTVTBJH-UHFFFAOYSA-N

Description

General description

Sodium cyanoborohydride, also known as sodium cyanotrihydridoborate, is a mild reducing agent that is stable in acidic conditions. It is widely used in the selective reduction of aryl aldehydes and ketones.

Application

Reagent for selective reductions.

Sodium cyanoborohydride is used as a reagent: 

• To convert the amino-functional Si₃N₄ surface to a reactive surface with aldehyde groups.
• For coupling amino-modified oligonucleotide probes.
• In the synthesis of a novel phenolate-bridged dilanthanum(III) complex of interest as a model for metalloproteins.
• In the reductive amination of aldehydes and ketones, and in the reductive alkylation of amines.

Safety Information

• pictograms: GHS02,GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H228,H260,H300 + H310 + H330,H314,H410
• pcodes: P210 - P231 + P232 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Skin Corr. 1B - Water-react 1
• supp_hazards: EUH032
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: 158.0 °F - closed cup
• flash_point_c: 70 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges