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180246

2-Naphthoic acid

Name: 2-Naphthoic acid
Brand: ALDRICH

98%

Synonym(s):

2-Naphthalenecarboxylic acid

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About This Item

Linear Formula:

C₁₀H₇CO₂H

CAS Number:

93-09-4

Molecular Weight:

172.18

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24850857

EC Number:

202-217-8

Beilstein/REAXYS Number:

972039

MDL number:

MFCD00004101

Assay:

98%

Form:

powder

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Properties

Quality Level

100

assay

98%

form

powder

mp

185-187 °C (lit.)

solubility

alcohol: soluble, diethyl ether: soluble, hot water: slightly soluble

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2ccccc2c1

InChI

1S/C11H8O2/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,(H,12,13)

InChI key

UOBYKYZJUGYBDK-UHFFFAOYSA-N

Description

General description

2-Naphthoic acid (NPA) is a noncompetitive N-methyl-D-aspartate (NMDA) receptor inhibitor. The fluorescence spectra and electronic absorption of 2-naphthoic acid was studied.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Inhibition of GluN2A-containing N-methyl-D-aspartate receptors by 2-naphthoic acid.

Han Yu et al.

Molecular pharmacology, 84(4), 541-550 (2013-07-23)

N-Methyl-D-aspartate (NMDA) receptors mediate excitatory synaptic transmission in the central nervous system and play important roles in synaptic development and plasticity, but also mediate glutamate neurotoxicity. Recently, 2-naphthoic acid (NPA) and its derivatives have been identified as allosteric, noncompetitive NMDA

An electronic spectral study of the influence of thermal and electronic processes on the determination of the excited singlet-state dissociation constants of 1-and 2-naphthoic acid.

Kovi PJ and Schulman SG.

Analytica Chimica Acta, 63(1), 39-52 (1973)

Discovery of 2-naphthoic acid monooxygenases by genome mining and their use as biocatalysts.

Toshiki Furuya et al.

ChemSusChem, 2(7), 645-649 (2009-06-30)

The large pool of cytochrome P450 (P450) open-reading frames identified in genome sequences has attracted much attention as a resource for new oxidation biocatalysts. P450 genes were cloned from genome-sequenced bacteria and coexpressed with putidaredoxin and its reductase genes to

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Global Trade Item Number

SKU	GTIN
180246-5G	04061838754820
180246-25G	04061838754813