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250260

Sigma-Aldrich

2-Naphthoyl chloride

98%

Synonym(s):

β-Naphthoyl chloride

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About This Item

Linear Formula:
C10H7COCl
CAS Number:
Molecular Weight:
190.63
Beilstein/REAXYS Number:
907776
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

form

solid

bp

160-162 °C/11 mmHg (lit.)

mp

50-52 °C (lit.)

SMILES string

ClC(=O)c1ccc2ccccc2c1

InChI

1S/C11H7ClO/c12-11(13)10-6-5-8-3-1-2-4-9(8)7-10/h1-7H

InChI key

XNLBCXGRQWUJLU-UHFFFAOYSA-N

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Related Categories

Application

2-Naphthoyl chloride has been used in:
  • preparation of amide derivatives of the amphetamine enantiomers
  • synthesis of 7-dimethylamino-2-methyl-3-naphthamido-phenothiazinium salt
  • modification of self-assembled monolayer formed on silica surface from ((((aminoethyl)amino)-methyl)phenethyl)trimethoxysilane

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B

wgk_germany

WGK 3

flash_point_f

235.4 °F

flash_point_c

113 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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I W Wainer et al.
Journal of pharmaceutical sciences, 73(8), 1162-1164 (1984-08-01)
A rapid and accurate method was developed for the determination of the enantiomeric composition of amphetamine preparations. Amide derivatives of the amphetamine enantiomers are first formed by using achiral 2-naphthoyl chloride. The resulting enantiomeric amides are then chromatographed on a
Formation and naphthoyl derivatization of aromatic aminosilane self-assembled monolayers: characterization by atomic force microscopy and ultraviolet spectroscopy.
Durfor CN, et al.
Langmuir, 10(1), 148-152 (1994)
Tagbo Emmanuel Ezenwa et al.
Dalton transactions (Cambridge, England : 2003), 47(47), 16938-16943 (2018-11-18)
Selenium and sulfur derivatives of lead(ii) acylchalcogourato complexes have been used to deposit PbSxSe1-x thin films by AACVD. By variation of the mole ratio of sulfur and selenium precursors in the aerosol feed solution the full range of compositions of
V L Lanchote et al.
Journal of chromatography. B, Biomedical applications, 685(2), 281-289 (1996-10-25)
Two methods were developed for the determination of mexiletine enantiomers in plasma samples suitable for studies on the stereoselective disposition of this drug. Both methods used fluorescence detection to improve sensitivity and selectivity. The direct enantioselective separation was based on
A chemically modified graphite electrode for electrocatalytic oxidation of reduced nicotinamide adenine dinucleotide based on a phenothiazine derivative, 3-?-naphthoyl-toluidine blue O.
Persson B.
J. Electroanal. Chem. Interfac. Electrochem., 287(1), 61-80 (1990)

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