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198250

Sigma-Aldrich

Rose bengal

certified by the Biological Stain Commission, Dye content ≥80 %

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Synonym(s):
4,5,6,7-Tetrachloro-2′,4′,5′,7′-tetraiodofluorescein disodium salt, Acid Red 94, Bengal Rose B sodium salt, Rose Bengal sodium salt
Empirical Formula (Hill Notation):
C20H2Cl4I4Na2O5
CAS Number:
Molecular Weight:
1017.64
Colour Index Number:
45440
Beilstein/REAXYS Number:
3645857
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

grade

certified by the Biological Stain Commission

form

powder

composition

Dye content, ≥80%

color

dark violet

solubility

H2O: 1 mg/mL

λmax

548 nm

ε (extinction coefficient)

≥90000 at 546-550 nm at 0.008 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[O-]C(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C2=C3C=C(I)C(=O)C(I)=C3Oc4c(I)c([O-])c(I)cc24

InChI

1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2

InChI key

UWBXIFCTIZXXLS-UHFFFAOYSA-L

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1 of 4

This Item
330000E4382861006
vibrant-m

198250

Rose bengal

vibrant-m

330000

Rose bengal

vibrant-m

E4382

Eosin Y disodium salt

vibrant-m

861006

Eosin B

grade

certified by the Biological Stain Commission

grade

-

grade

certified by the Biological Stain Commission

grade

certified by the Biological Stain Commission

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

composition

Dye content, ≥80%

composition

Dye content, 95%

composition

Dye content, ≥90%

composition

Dye content, 90%

ε (extinction coefficient)

≥90000 at 546-550 nm at 0.008 g/L

ε (extinction coefficient)

≥ 3000 at 350-354 nm, ≥12000 at 311-315 nm, ≥32000 at 262-266 nm, ≥32000 at 513-517 nm, ≥98000 at 546-550 nm at 0.04 g/L (H2O + 1ml 1% Na2CO3)

ε (extinction coefficient)

-

ε (extinction coefficient)

-

solubility

H2O: 1 mg/mL

solubility

-

solubility

H2O: 1 mg/mL

solubility

H2O: 1 mg/mL, clear, red

General description

Rose Bengal is the sodium salt of tetraiodotetrachlorouorescein, C20H2O5I4Cl4Na2. It is an anionic water-soluble xanthene dye.

Application

Rose bengal has several microbilogical staining applications including:
  • Conn′s technique for bacteria in soil and Kreyberg′s stain for keratin and mucus
  • counterstaining hematoxylin
  • staining cellular inclusions, together with Bismark brown



Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Steffanie Heindl et al.
The Journal of experimental medicine, 218(8) (2021-05-27)
Neuroinflammation is an emerging focus of translational stroke research. Preclinical studies have demonstrated a critical role for brain-invading lymphocytes in post-stroke pathophysiology. Reducing cerebral lymphocyte invasion by anti-CD49d antibodies consistently improves outcome in the acute phase after experimental stroke models.
J Varga et al.
Studies in mycology, 69(1), 1-17 (2011-09-06)
Four new species, Aspergillus eucalypticola, A. neoniger, A. fijiensis and A. indologenus are described and illustrated. Aspergillus eucalypticola was isolated from Eucalyptus leaf from Australia, and is related to A. tubingensis and A. costaricaensis, but could clearly be distinguished from
Priyanka S Bapat et al.
Frontiers in cellular and infection microbiology, 11, 713092-713092 (2021-09-21)
Fungal infections are increasing in prevalence worldwide. The paucity of available antifungal drug classes, combined with the increased occurrence of multidrug resistance in fungi, has led to new clinical challenges in the treatment of fungal infections. Candida auris is a
Christopher Kesten et al.
The EMBO journal, 38(24), e101822-e101822 (2019-11-19)
Environmental adaptation of organisms relies on fast perception and response to external signals, which lead to developmental changes. Plant cell growth is strongly dependent on cell wall remodeling. However, little is known about cell wall-related sensing of biotic stimuli and
Rebecca Sadler et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(5), 1162-1173 (2020-01-01)
Recovery after stroke is a multicellular process encompassing neurons, resident immune cells, and brain-invading cells. Stroke alters the gut microbiome, which in turn has considerable impact on stroke outcome. However, the mechanisms underlying gut-brain interaction and implications for long-term recovery

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