22135

(+)-Cedrol

≥99.0% (sum of enantiomers, GC)

• Synonym(s): (1S,2R,5S,7R,8R)-2,6,6,8-Tetramethyltricyclo[5.3.1.0^1.5]undecan-8-ol
• Empirical Formula (Hill Notation): C₁₅H₂₆O
• CAS Number: 77-53-2
• Molecular Weight: 222.37
• Beilstein/REAXYS Number: 2206347
• EC Number: 201-035-6
• MDL number: MFCD00062952
• UNSPSC Code: 12352212
• PubChem Substance ID: 57647965
• NACRES: NA.22

Properties

• assay: ≥99.0% (sum of enantiomers, GC)
• form: solid
• optical activity: [α]20/D +10.5±1°, c = 5% in chloroform
• bp: 273 °C (lit.)
• mp: 82-86 °C; 86-87 °C (lit.)
• functional group: hydroxyl
• SMILES string: C[C@@H]1CC[C@H]2C(C)(C)[C@H]3C[C@@]12CC[C@@]3(C)O
• InChI: 1S/C15H26O/c1-10-5-6-11-13(2,3)12-9-15(10,11)8-7-14(12,4)16/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m1/s1
• InChI key: SVURIXNDRWRAFU-OGMFBOKVSA-N

Description

General description

(+)-Cedrol is a crystalline hydrated product of α-cedrene, which is a sesquiterpene found in cedar-wood oil. It can be used as a fragrance ingredient in cosmetics, shampoos, and soaps as well as in non-cosmetic products such as cleaners and detergents. (±) Cedrol can be synthesized by intramolecular Diels-Alder reaction of alkyl cyclopentadiene.

Application

(+)-Cedrol can be used as a starting material for the preparation of cedryl acetate by acetylation using acetic anhydride in the presence of an acid catalyst. It can also be incorporated as a precursor for the total synthesis of rare illicium sesquiterpene (+)-pseudoanisatin via selective C-H bond functionalization.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)