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MilliporeSigma

254916

Sigma-Aldrich

7,8-Dihydroxy-6-methoxycoumarin

98%

Synonym(s):

Fraxetin

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1 G
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1 G
$88.50

About This Item

Empirical Formula (Hill Notation):
C10H8O5
CAS Number:
Molecular Weight:
208.17
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

$88.50

List Price$177.00Save 50%

In StockDetails


Request a Bulk Order

Quality Level

assay

98%

form

powder

mp

230-231 °C (lit.)

SMILES string

COc1cc2C=CC(=O)Oc2c(O)c1O

InChI

1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3

InChI key

HAVWRBANWNTOJX-UHFFFAOYSA-N

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Po-Lin Kuo et al.
International immunopharmacology, 6(7), 1167-1175 (2006-05-23)
The survival of osteoblast cells is one of the determinants of the development of osteoporosis in patients with inflamed synovium, such as in rheumatoid arthritis (RA). By means of alkaline phosphatase (ALP) activity and osteocalcin ELISA assay, we have shown
Joana Terés et al.
Plant, cell & environment, 42(8), 2384-2398 (2019-04-25)
High soil carbonate limits crop performance especially in semiarid or arid climates. To understand how plants adapt to such soils, we explored natural variation in tolerance to soil carbonate in small local populations (demes) of Arabidopsis thaliana growing on soils
Phuong Thien Thuong et al.
Biological & pharmaceutical bulletin, 32(9), 1527-1532 (2009-09-02)
Atherosclerosis is main cause of arteriosclerosis. The pivotal role of low-density lipoprotein (LDL) oxidation in atherogenesis suggests antioxidants may help prevent cardiovascular disease. Fraxinus rhynchophylla DENCE (Oleaceae) is a traditional medicinal plant from East Asia. During the course of characterizing
S Martín-Aragón et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 52(1-2), 55-59 (1997-01-01)
We have evaluated the effects of an oral treatment of mice with fraxetin (25 mg/kg for 30 days) on the glutathione system (GSH, GSSG, and GSSG/GSH ratio as stress index), glutathione reductase (GR) and glutathione peroxidase (GPx) in liver supernatants
B Fernandez-Puntero et al.
Biological & pharmaceutical bulletin, 24(7), 777-784 (2001-07-18)
The aim of this paper was to study the influence of Fraxetin (7,8-dihydroxy-6-methoxv coumarin) treatment in a Drosophila melanogaster experimental model, analyzing several parameters in normal situations and instances of induced oxidative stress. Fraxetin treatment was introduced at different ages.

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