319732

Perfluoro-1-butanesulfonyl fluoride

96%

• Synonym(s): NfF, Nonafluorobutanesulfonyl fluoride
• Linear Formula: CF₃(CF₂)₃SO₂F
• CAS Number: 375-72-4
• Molecular Weight: 302.09
• EC Number: 206-792-6
• MDL number: MFCD00007422
• UNSPSC Code: 12352100
• PubChem Substance ID: 24859184
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 96%
• form: liquid
• reaction suitability: reaction type: click chemistry
• refractive index: n20/D 1.3 (lit.)
• bp: 64 °C (lit.)
• density: 1.682 g/mL at 25 °C (lit.)
• SMILES string: FC(F)(F)C(F)(F)C(F)(F)C(F)(F)S(F)(=O)=O
• InChI: 1S/C4F10O2S/c5-1(6,3(9,10)11)2(7,8)4(12,13)17(14,15)16
• InChI key: LUYQYZLEHLTPBH-UHFFFAOYSA-N

Description

Application

Perfluoro-1-butanesulfonyl fluoride (NfF) reacts with alcohols, including phenols, to yield nonafluorobutanesulfonate esters (nonaflates). Nonaflates can be used as electrophiles in several palladium-catalyzed cross coupling reactions and in Buchwald-Hartwig amination.
NfF can also be used to prepare aryl nonaflates by reacting with corresponding aryloxysilanes in the presence of fluoride ion.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles