804401

PyFluor

• Synonym(s): 2-Pyridinesulfonyl Fluoride
• Empirical Formula (Hill Notation): C₅H₄FNO₂S
• CAS Number: 878376-35-3
• Molecular Weight: 161.15
• MDL number: MFCD09265513
• UNSPSC Code: 12352101
• PubChem Substance ID: 329768867
• NACRES: NA.22

Properties

• assay: 95% (HPLC)
• Quality Level: 100
• form: solid
• mp: 29-34 °C
• storage temp.: 2-8°C
• SMILES string: O=S(C1=CC=CC=N1)(F)=O
• InChI: 1S/C5H4FNO2S/c6-10(8,9)5-3-1-2-4-7-5/h1-4H
• InChI key: FCFXLXGZHDHJLB-UHFFFAOYSA-N

Description

Application

2-pyridinesulfonyl fluoride can be used for the deoxyfluorination of primary and secondary alcohols in combination with an amidine or guanidine base. In comparison with other common deoxyfluorination reagents, for example, DAST exhibits less elimination side products in direct comparison on certain substrates.

Legal Information

PyFluor: A Low-Cost, Stable, and Selective Deoxyfluorination Reagent

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable