338257

Isobutylmagnesium bromide solution

2.0 M in diethyl ether

• Synonym(s): iBuMgBr solution
• Linear Formula: (CH₃)₂CHCH₂MgBr
• CAS Number: 926-62-5
• Molecular Weight: 161.32
• MDL number: MFCD00075126
• UNSPSC Code: 12352103
• PubChem Substance ID: 24860530
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 100
• reaction suitability: reaction type: Grignard Reaction
• concentration: 2.0 M in diethyl ether
• density: 0.941 g/mL at 25 °C
• SMILES string: CC(C)C[Mg]Br
• InChI: 1S/C4H9.BrH.Mg/c1-4(2)3;;/h4H,1H2,2-3H3;1H;/q;;+1/p-1
• InChI key: CMWBEISSZHZIMU-UHFFFAOYSA-M

Description

Application

Isobutylmagnesium bromide (iBuMgBr) is a general Grignard reagent used in the total synthesis of (+)-rishirilide B, glucolipsin A, and (+)-juvabione. It can also be used as a reagent in the synthesis of pyrrolidine-based influenza neuraminidase (NA) inhibitors.

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H224,H302,H315,H318,H336
• pcodes: P210 - P233 - P280 - P301 + P312 - P305 + P351 + P338 - P403 + P233
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Irrit. 2 - STOT SE 3
• target_organs: Central nervous system
• supp_hazards: EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: -29.2 °F - closed cup
• flash_point_c: -34 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves