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Sigma-Aldrich

Isobutylmagnesium bromide solution

2.0 M in diethyl ether

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Synonym(s):
iBuMgBr solution
Linear Formula:
(CH3)2CHCH2MgBr
CAS Number:
Molecular Weight:
161.32
MDL number:
PubChem Substance ID:
NACRES:
NA.22

form

liquid

Quality Level

reaction suitability

reaction type: Grignard Reaction

concentration

2.0 M in diethyl ether

density

0.941 g/mL at 25 °C

SMILES string

CC(C)C[Mg]Br

InChI

1S/C4H9.BrH.Mg/c1-4(2)3;;/h4H,1H2,2-3H3;1H;/q;;+1/p-1

InChI key

CMWBEISSZHZIMU-UHFFFAOYSA-M

Application

Isobutylmagnesium bromide (iBuMgBr) is a general Grignard reagent used in the total synthesis of (+)-rishirilide B, glucolipsin A, and (+)-juvabione. It can also be used as a reagent in the synthesis of pyrrolidine-based influenza neuraminidase (NA) inhibitors.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

4.3 - Hazardous materials, which set free flammable gases upon contact with water

wgk_germany

WGK 3

flash_point_f

-29.2 °F - closed cup

flash_point_c

-34 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves


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