339601

1-Bromo-4-(trifluoromethoxy)benzene

99%

• Linear Formula: BrC₆H₄OCF₃
• CAS Number: 407-14-7
• Molecular Weight: 241.01
• EC Number: 206-979-2
• MDL number: MFCD00040834
• UNSPSC Code: 12352100
• PubChem Substance ID: 24860653
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• form: liquid
• refractive index: n20/D 1.461 (lit.)
• bp: 80 °C/50 mmHg (lit.)
• density: 1.622 g/mL at 25 °C (lit.)
• functional group: bromo; fluoro
• SMILES string: FC(F)(F)Oc1ccc(Br)cc1
• InChI: 1S/C7H4BrF3O/c8-5-1-3-6(4-2-5)12-7(9,10)11/h1-4H
• InChI key: SEAOBYFQWJFORM-UHFFFAOYSA-N

Description

General description

1-Bromo-4-(trifluoromethoxy)benzene on treatment with lithium diisopropylamide (LIDA) at -100°C gives 5-bromo-2-(trifluoromethoxy)phenyllithium and at -75°C it eliminates lithium bromide, thus generating 1,2-dehydro-4-(trifluoromethoxy)benzene.

Application

1-Bromo-4-(trifluoromethoxy)benzene was used in the synthesis of 4-{[4-[(2-ethylhexyloxy)-6-(4-morpholinylmethyl)-4-trifluoromethyl][1,1-biphenyl]-3-yl]methyl}morpholine.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315
• pcodes: P264 - P280 - P302 + P352 - P332 + P313 - P362 + P364
• Hazard Classifications: Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter