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357898

Sigma-Aldrich

Serinol

98%

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Synonym(s):
2-Amino-1,3-propanediol
Linear Formula:
HOCH2CH(NH2)CH2OH
CAS Number:
Molecular Weight:
91.11
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

bp

277 °C (lit.)

mp

52-55 °C (lit.)

SMILES string

NC(CO)CO

InChI

1S/C3H9NO2/c4-3(1-5)2-6/h3,5-6H,1-2,4H2

InChI key

KJJPLEZQSCZCKE-UHFFFAOYSA-N

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This Item
S4250PHR1103252859
Serinol 98%

Sigma-Aldrich

357898

Serinol

-
D-Serine ≥98% (TLC)

Sigma-Aldrich

S4250

D-Serine

-
L-Serine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1103

L-Serine

-
Tris(hydroxymethyl)aminomethane ACS reagent, ≥99.8%

Sigma-Aldrich

252859

Tris(hydroxymethyl)aminomethane

Essential Grade
bp

277 °C (lit.)

bp

-

bp

-

bp

219-220 °C/10 mmHg (lit.)

mp

52-55 °C (lit.)

mp

-

mp

222 °C (dec.) (lit.)

mp

167-172 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

General description

Serinol activates toxin production in the attenuated cultures of Helminthosporium sacchari. Preparation of polyesters derived from serinol is reported.

Application

Serinol may be used to prepare the artificial nucleic acids. It may be used in the synthesis of N-acylated serinol and C16-serinol affinity gel.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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F Pinkerton et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(11), 4007-4011 (1976-11-01)
Successive transfer in synthetic medium of spores and mycelial fragments from original toxin-producing cultures of Helminthosporium sacchari results in attenuated cultures which do not produce the host-specific toxin helminthosporoside. When attenuated cultures are grown on material obtained from the water
Hiroyuki Asanuma et al.
Chemical record (New York, N.Y.), 14(6), 1055-1069 (2014-08-30)
In this account, we demonstrate a new methodology for the de novo design of functional oligonucleotides with the acyclic scaffolds threoninol and serinol. Four functional motifs-wedge, interstrand-wedge, dimer, and cluster-have been prepared from natural DNA or RNA and functional base
Margherita Bodini et al.
mSphere, 5(5) (2020-09-18)
Invasive meningococcal disease (IMD) caused by Neisseria meningitidis is a significant cause of morbidity and mortality worldwide. In Finland, the incidence rate of IMD is low, with meningococcal serogroup B (MenB) accounting for around one-third of IMD cases annually. The
Gea Prioglio et al.
Polymers, 12(4) (2020-04-25)
The ultimate properties and resistance to fracture of nanocomposites based on poly(1,4-cis-isoprene) from Hevea Brasiliensis (natural rubber, NR) and a high surface area nanosized graphite (HSAG) were improved by using HSAG functionalized with 2-(2,5-dimethyl-1H-pyrrol-1-yl)propane-1,3-diol (serinol pyrrole) (HSAG-SP). The functionalization reaction
E Bieberich et al.
The Journal of biological chemistry, 275(1), 177-181 (2000-01-05)
A novel structural analog of ceramide was synthesized by N-acylation of serinol (2-amino-1,3-propanediol) and studied for its effects on glycolipid biosynthesis and cell differentiation of neuroblastoma cells. Incubation with N-palmitoylated serinol (C16-serinol) increased the concentration of endogenous ceramide by 50-80%

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