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410896

Sigma-Aldrich

2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone

98%

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Synonym(s):
1-[4-(2-Hydroxyethoxy)phenyl]-2-hydroxy-2-methyl-1-propan-1-one, 2-Hydroxy-1-[4-(2-hydroxyethoxy)phenyl]-2-methyl-1-propanone, 2-Hydroxy-2-methyl-1-[4-(2-hydroxyethoxy)phenyl]propan-1-one, 4-(2-Hydroxyethoxy)phenyl 2-hydroxy-2-propyl ketone
Linear Formula:
HOCH2CH2OC6H4COC(CH3)2OH
CAS Number:
Molecular Weight:
224.25
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

Assay

98%

mp

88-90 °C (lit.)

SMILES string

CC(C)(O)C(=O)c1ccc(OCCO)cc1

InChI

1S/C12H16O4/c1-12(2,15)11(14)9-3-5-10(6-4-9)16-8-7-13/h3-6,13,15H,7-8H2,1-2H3

InChI key

GJKGAPPUXSSCFI-UHFFFAOYSA-N

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This Item
405655405639194433
mp

88-90 °C (lit.)

mp

-

mp

74-76 °C (lit.)

mp

107 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

Application

2-Hydroxy-4′-(2-hydroxyethoxy)-2-methylpropiophenone can be used as a photo-initiator to synthesize:
  • Polyacrylamide-grafted chitosan nanoparticles by copolymerization of acrylamide and chitosan nanoparticles.
  • Hydrophobic polyurethane sponge through thiol–ene Click reaction.

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

not determined

Flash Point(C)

not determined

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jiangya Ma et al.
Carbohydrate polymers, 151, 565-575 (2016-07-31)
In the present work, a new flocculant, polyacrylamide-grafted chitosan nanoparticles (NCS-g-PAM), was synthesized by the copolymerization of acrylamide (AM) and chitosan nanoparticle (NCS) under ultraviolet irradiation using 2-hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone as photo-initiator. The NCS was prepared by the ionic gelation between chitosan
Xin Zhao et al.
Acta biomaterialia, 49, 66-77 (2016-11-09)
Development of natural protein-based fibrous scaffolds with tunable physical properties and biocompatibility is highly desirable to construct three-dimensional (3D), fully cellularized scaffolds for wound healing. Herein, we demonstrated a simple and effective technique to construct electrospun 3D fibrous scaffolds for
Rami El Assal et al.
Scientific reports, 6, 39144-39144 (2016-12-23)
Cancer cells have been increasingly grown in pharmaceutical research to understand tumorigenesis and develop new therapeutic drugs. Currently, cells are typically grown using two-dimensional (2-D) cell culture approaches, where the native tumor microenvironment is difficult to recapitulate. Thus, one of
Deepak Kumar et al.
Cell transplantation, 25(12), 2213-2220 (2016-07-28)
Nucleus pulposus (NP) tissue damage can induce detrimental mechanical strain on the biomechanical performance of intervertebral discs (IVDs), causing subsequent disc degeneration. A novel, photocurable, injectable, synthetic polymer hydrogel (pHEMA-co-APMA grafted with PAA) has already demonstrated success in encapsulating and
Justin J Y Tan et al.
Biomaterials science, 6(6), 1347-1357 (2018-04-25)
Interaction between cells and the extracellular environment plays a vital role in cellular development. The mechanical property of a 3-dimensional (3D) culture can be modified to mimic in vivo conditions. Dermal papilla (DP) cells are shown to gradually lose their

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