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435457

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

average Mn ~4,400

Synonym(s):
Pluronic® L-121, PEG-PPG-PEG
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

vapor density

>1 (vs air)

Quality Level

vapor pressure

<0.3 mmHg ( 20 °C)

form

viscous liquid

mol wt

average Mn ~4,400

composition

PEG, 30 wt. %

refractive index

n20/D 1.454

surface tension

33 dyn/cm, 25 °C, 0.1 wt. % in H2O

viscosity

1,200 cP(25 °C, Brookfield)(lit.)

transition temp

cloud point 14 °C (1 wt. % aqueous solution)
softening point 5 °C

density

1.006 g/mL at 25 °C

HLB

1.0 - 7.0

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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This Item
435449435406435465
mol wt

average Mn ~4,400

mol wt

average Mn ~2,900

mol wt

average Mn ~1,100

mol wt

average Mn ~5,800

viscosity

1,200 cP(25 °C, Brookfield)(lit.)

viscosity

850 cP(25 °C, Brookfield)(lit.)

viscosity

175 cP(25 °C, Brookfield)(lit.)

viscosity

350 cP(60 °C, Brookfield)(lit.)

transition temp

cloud point 14 °C (1 wt. % aqueous solution), softening point 5 °C

transition temp

cloud point 58 °C (1 wt. % aqueous solution)

transition temp

softening point −32 °C, cloud point 37 °C (1 wt. % aqueous solution)

transition temp

Tm (DSC) 39 °C (at peak), cloud point 90 °C (1 wt. % aqueous solution)

density

1.006 g/mL at 25 °C

density

1.05 g/mL at 25 °C

density

1.018 g/mL at 25 °C

density

1.018 g/mL at 25 °C

HLB

1.0 - 7.0

HLB

12.0 - 18.0

HLB

1.0 - 7.0

HLB

7 - 9

Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.

Features and Benefits

Surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.

Physical form

Terminal primary dihydroxy-functional oligomer.

Legal Information

Pluronic is a registered trademark of BASF

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
A N Sklifas et al.
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The adsorption abilities of the perfluorocarbon emulsion stabilized by Proxanol 268 were investigated in vitro and in vivo. In vitro, the saturation point for the blood plasma proteins was nearly reached after five minutes of incubation of the emulsion with
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Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
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Biomaterials, 33(33), 8613-8624 (2012-08-23)
Drug resistance is a main obstacle for the successful chemotherapy of lung cancer. In this work, a new co-delivery system, P85-PEI/TPGS/PTX/shSur complex nanoparticles (PTPNs), to overcome paclitaxel (PTX) resistance in A549 human lung cancer was designed and developed. The experimental

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