56413
2-Pyridinol 1-oxide
≥98.0% (N)
Synonym(s):
1-Hydroxy-2-pyridone, 2-Hydroxypyridine 1-oxide, HOPO
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About This Item
Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
Molecular Weight:
111.10
Beilstein/REAXYS Number:
1422545
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
assay
≥98.0% (N)
form
solid
mp
147-152 °C
SMILES string
Oc1cccc[n+]1[O-]
InChI
1S/C5H5NO2/c7-5-3-1-2-4-6(5)8/h1-4,7H
InChI key
JVHZMYAXZUIZKS-UHFFFAOYSA-N
Related Categories
General description
2-Pyridinol 1-oxide (HOPO) is a peptide coupling agent used as a subsititue for HOBt. It can form stable chelate complexes with transition metal ions.
Application
2-Pyridinol 1-oxide can be used:
- To fabricate gold electrodes for the electrochemical determination of europium using cyclic voltammetry.
- To prepare polymeric nickel (II) complex of 2-hydroxypyridine-N-oxide.
- In the synthesis of 1-methoxypyrid-4-one in the presence of sodium methoxide and methyl toluene-9-sulphonate.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
212.0 °F - closed cup
flash_point_c
100 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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This work presents for the first time the electrochemical determination of europium using cyclic voltammetry at gold electrodes modified with 2-pyridinol-1-oxide. A well-defined oxidation peak was observed in cyclic voltammetry as a result of the oxidation of the europium at
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