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PAMAM Dendrimer Kit, generations 4-7

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eCl@ss:
32161000
NACRES:
NA.23

description

amino surface groups

feature

core type ethylenediamine core (2-carbon core)

storage temp.

2-8°C

Related Categories

General description

Ethylenediamine-core poly(amidoamine) (PAMAM) dendrimers are highly branched, “tree-like” core-shell nanostructures made up of amide and amine functional subunits.

Application

PAMAM Dendrimer Kit, generations 4-7 can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers, allowing to mix otherwise immiscible materials.

Packaging

unit weight includes solvent

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

Kit Components Also Available Separately

Product No.
Description
SDS

  • 412449PAMAM dendrimer, ethylenediamine core, generation 4.0 solution, 10 wt. % in methanol 1 gSDS

  • 536709PAMAM dendrimer, ethylenediamine core, generation 5.0 solution, 5 wt. % in methanol 1 gSDS

  • 536717PAMAM dendrimer, ethylenediamine core, generation 6.0 solution, 5 wt. % in methanol 1 gSDS

  • 536725PAMAM dendrimer, ethylenediamine core, generation 7.0 solution, 5 wt. % in methanol 1 gSDS

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup


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PAMAM dendrimer: a pH-controlled nanosponge
Maiti PK
Canadian Journal of Chemistry, 95(9), 991-998 (2017)
Heck reactions catalyzed by PAMAM-dendrimer encapsulated Pd (0) nanoparticles
Rahim EH, et al.
Nano Letters, 1(9), 499-501 (2001)
Poly (amidoamine) dendrimers as a pharmaceutical excipient. Are we there yet?
Otto DP and De Villiers MM
Journal of Pharmaceutical Sciences, 107(1), 75-83 (2018)
Esen Efeoglu et al.
The Analyst, 142(20), 3848-3856 (2017-09-13)
Although consumer exposure to nanomaterials is ever increasing, with potential increased applications in areas such as drug and/or gene delivery, contrast agents and diagnosis, the determination of the cyto- and geno-toxic effects of nanomaterials on human health and the environment

Articles

Environmental concerns are driving the replacement of volatile organic solvents by water and aqueous mixtures. This change often creates challenges because many organic molecules show low water solubility.

The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.

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