674427

11-Mercaptoundecanoic acid

98%

• Synonym(s): MUA, MUDA
• Linear Formula: HS(CH₂)₁₀CO₂H
• CAS Number: 71310-21-9
• Molecular Weight: 218.36
• MDL number: MFCD00022096
• UNSPSC Code: 12352103
• PubChem Substance ID: 329760593
• NACRES: NA.23

Properties

• Quality Level: 100
• assay: 98%
• form: solid
• mp: 46-50 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: OC(=O)CCCCCCCCCCS
• InChI: 1S/C11H22O2S/c12-11(13)9-7-5-3-1-2-4-6-8-10-14/h14H,1-10H2,(H,12,13)
• InChI key: GWOLZNVIRIHJHB-UHFFFAOYSA-N

Description

General description

11-mercaptoundecanoic acid (MUA) has long alkane chains and carboxyl containing thiols that are highly packed and form a self-assembled monolayer (SAM). It modifies the surface of nanoparticles to facilitate their dispersion into water and solvent based mediums.

Application

MUA is used for the carboxylic acid functionalization of 1-dodecanethiol-protected gold nanoparticles (AuNPs) by Murray place-displacement reaction generally utilized in biomedical applications. It can also be used to modify the surface of platinum nanoparticles (PtNPs) by creating a ligand nano-assembly with a high surface coverage for use in surface-enhanced Raman spectroscopy (SERS). A single cell biochip platform can be developed utilizing a cell attachment technique with MUA forming a SAM that was attached to single cells. MUA may be used to prepare a tetrafluorophenyl-activated ester self-assembled monolayer to immobilize amine-modified oligonucleotides and DNA. It is also used to create 3D-assembled gold nanostructures for plasmonic biosensors.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: No data available
• flash_point_c: No data available
• ppe: dust mask type N95 (US), Eyeshields, Gloves