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677418

Sigma-Aldrich

Hydroxyapatite

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

Synonym(s):
Calcium phosphate tribasic, Calcium hydroxyphosphate, HAp, Hydroxylapatite, Tribasic calcium phosphate
Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
Molecular Weight:
502.31
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Assay

≥97%

form

nanopowder
solid

surface area

>9.4 m2/g
>9.4 m2/g

particle size

<200 nm (BET)

mp

1100 °C (lit.)

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

Inchi Key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Hydroxyapatite nanopowder, &lt;200&#160;nm particle size (BET), &#8805;97%, synthetic

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677418

Hydroxyapatite

Hydroxyapatite reagent grade, powder, synthetic

Sigma-Aldrich

289396

Hydroxyapatite

Hydroxyapatite nanopowder, &lt;200&#160;nm particle size (BET), contains 5&#160;wt. % silica as dopant, synthetic

Sigma-Aldrich

693863

Hydroxyapatite

Hydroxyapatite synthetic, 99.8% trace metals basis (excludes Mg)

Sigma-Aldrich

574791

Hydroxyapatite

assay

≥97%

assay

-

assay

-

assay

99.8% trace metals basis (excludes Mg)

form

nanopowder, solid

form

powder, solid

form

nanopowder, solid

form

solid

mp

1100 °C (lit.)

mp

1100 °C (lit.)

mp

1100 °C (lit.)

mp

1100 °C (lit.)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

particle size

<200 nm (BET)

particle size

-

particle size

<200 nm (BET)

particle size

-

surface area

>9.4 m2/g

surface area

-

surface area

BET surf. area 10-15 m2/g (typical)

surface area

-

General description

Hydroxyapatite(HA) belongs to the family of Ca apatite which resembles natural bone in both structure and chemical composition. It can be prepared by various techniques such as chemical precipitation, hydrothermal, electrospinning, and self-propagating combustion. It is widely used as an implant material for bone regeneration, a drug carrier, and a gene delivery system due to its bioactive and biocompatible nature.

Application

Nanoscale hydroxyapatite particles can be used to prepare bone tissue engineering materials due to their slow biodegradability in situ, good osteoconductive and osteoinductive capabilities.

Poly (sodium 4-styrene sulfonate)-modified hydroxyapatite nanoparticles can be used as a drug carrier for vancomycin. Hydroxyapatite nanoparticles control the release of antibiotics after the implantation of a scaffold in the body.

Porous hydroxyapatite microspheres exhibit a high adsorptive capacity for heavy metals and can be used for the treatment of heavy metal contaminated water.

Features and Benefits

  • Bioactive and biocompatible
  • Good mechanical strength
  • Porous structure
  • Osteoconductive and osteointegrative properties

Legal Information

Product of Engi-Mat Co.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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