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21223

Sigma-Aldrich

Hydroxyapatite

purum p.a., ≥90% (as Ca3(PO4)2, KT)

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Synonym(s):
Calcium phosphate hydroxide, Durapatite, Hydroxylapatite
Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
Molecular Weight:
502.31
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

grade

purum p.a.

Quality Level

assay

≥90% (as Ca3(PO4)2, KT)

form

powder

impurities

≤5% water (KFT)

loss

≤10% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤500 mg/kg
sulfate (SO42-): ≤2000 mg/kg

cation traces

Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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1 of 4

This Item
900204677418289396
vibrant-m

21223

Hydroxyapatite

vibrant-m

900204

Hydroxyapatite

vibrant-m

677418

Hydroxyapatite

vibrant-m

289396

Hydroxyapatite

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

assay

≥90% (as Ca3(PO4)2, KT)

assay

-

assay

≥97%

assay

-

anion traces

chloride (Cl-): ≤500 mg/kg, sulfate (SO42-): ≤2000 mg/kg

anion traces

-

anion traces

-

anion traces

-

impurities

≤5% water (KFT)

impurities

-

impurities

-

impurities

-

cation traces

Cd: ≤5 mg/kg, Cu: ≤20 mg/kg, Ni: ≤5 mg/kg, Zn: ≤10 mg/kg, Co: ≤5 mg/kg, Pb: ≤5 mg/kg

cation traces

-

cation traces

-

cation traces

-

General description

Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.
Hydroxyapatite is a bioceramic mainly found in minerals of bone and teeth. Due to its high biocompatibility and similarity with inorganic components found in hard tissues, it is mainly used to produce biocomposites and prostheses for bones and teeth replacement.

Application

Hydroxyapatite may be used in the preparation of bioceramic specimens by incorporation of a small amount of silicon (0.4wt%) into the structure of hydroxyapatite. It may be used for the preparation of porous microstructures, having important prosthetic applications.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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Sigma-Aldrich

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USP

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Tribasic calcium phosphate

Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
Hydroxyapatite synthesis and the benefits of its blend with calcium aluminate cement.
Oliveira IR, et al.
Ceramics International, 42(2), 2542-2549 (2016)
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute

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