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21223

Sigma-Aldrich

Hydroxyapatite

purum p.a., ≥90% (as Ca3(PO4)2, KT)

Synonym(s):

Calcium phosphate hydroxide, Durapatite, Hydroxylapatite

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About This Item

Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
1306-06-5
Molecular Weight:
502.31
EC Number:
215-145-7
MDL number:
MFCD00010904
UNSPSC Code:
12352300
PubChem Substance ID:
57647915
NACRES:
NA.21

grade

purum p.a.

Quality Level

100

assay

≥90% (as Ca3(PO4)2, KT)

form

powder

impurities

≤5% water (KFT)

loss

≤10% loss on ignition, 800 °C

anion traces

chloride (Cl-): ≤500 mg/kg
sulfate (SO42-): ≤2000 mg/kg

cation traces

Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤10 mg/kg

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

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General description

Bone and tooth implant materials have been prepared from polycrystalline hydroxyapatite. The compressive, flexural, torsional and dynamic torsional strengths of polycrystalline hydroxyapatite were investigated. Electrophoretic deposition of hydroxyapatite on to flat titanium plate material has been studied.
Hydroxyapatite is a bioceramic mainly found in minerals of bone and teeth. Due to its high biocompatibility and similarity with inorganic components found in hard tissues, it is mainly used to produce biocomposites and prostheses for bones and teeth replacement.

Application

Hydroxyapatite may be used in the preparation of bioceramic specimens by incorporation of a small amount of silicon (0.4wt%) into the structure of hydroxyapatite. It may be used for the preparation of porous microstructures, having important prosthetic applications.

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK5328
BCCK8478
BCCK5856
BCCK6627
BCCH1305

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Hydroxyapatite synthesis and the benefits of its blend with calcium aluminate cement.
Oliveira IR, et al.
Ceramics International, 42(2), 2542-2549 (2016)
Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Bjarke Viberg et al.
Acta orthopaedica, 84(3), 254-259 (2013-04-19)
Elderly patients with displaced femoral neck fractures are commonly treated with a hemiarthroplasty (HA), but little is known about the long-term failure of this treatment. We compared reoperation rates for patients aged at least 75 years with displaced femoral neck
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