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753645

Sigma-Aldrich

Gold nanoparticles

50 nm diameter, OD 1, stabilized suspension in 0.1 mM PBS, reactant free

Synonym(s):

Au NP, Gold colloid

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About This Item

MDL number:
UNSPSC Code:
12352302
PubChem Substance ID:
NACRES:
NA.23

Quality Level

form

nanoparticles
suspension

packaging

poly bottle of 100 mL
poly bottle of 25 mL

storage condition

do not freeze

concentration

~3.5E+10 particles/mL

OD

1

diameter

50 nm

λmax

531-535 nm

PDI

<0.2

storage temp.

2-8°C

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Gold nanoparticles may be prepared by reduction of metal salt precursors with reducing agents, such as by citrate reduction of HAuCl4 in water.

Application

Gold nanoparticles 50 nm diameter, OD 1, stabilization suspension in 0.1 mM PBS, reactant free can be potentially used as a theranostic agent for the treatment of COVID-19. It may also be used in the fabrication of fiber-optic biosensors for low cost and fast detection of SARS-CoV-2.
Gold nanoparticles are used in a wide range of applications. It may be used :
  • As conductors in printable inks,
  • In Photodynamic therapy,
  • In drug delivery and biomarkers,
  • As calorimetric sensor,
  • In biological imaging,

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Aggregation and adhesion of gold nanoparticles in phosphate buffered saline
Du S, et al.
Journal of Nanoparticle Research, 14 null
Gang Peng et al.
Nature nanotechnology, 4(10), 669-673 (2009-10-08)
Conventional diagnostic methods for lung cancer are unsuitable for widespread screening because they are expensive and occasionally miss tumours. Gas chromatography/mass spectrometry studies have shown that several volatile organic compounds, which normally appear at levels of 1-20 ppb in healthy
Tanya Stuchinskaya et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 10(5), 822-831 (2011-04-02)
A 4-component antibody-phthalocyanine-polyethylene glycol-gold nanoparticle conjugate is described for use as a potential drug for targeted photodynamic cancer therapy. Gold nanoparticles (4 nm) were stabilised with a self-assembled layer of a zinc-phthalocyanine derivative (photosensitiser) and a heterobifunctional polyethylene glycol. Anti-HER2
Gold Nanoparticle Sensor for the Visual Detection of Pork Adulteration in Meatball Formulation
Ali ME, et al.
Journal of Nanomaterials (2012)
Steven D Perrault et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(25), 11194-11199 (2010-06-11)
Many small molecular anticancer agents are often ineffective at detecting or treating cancer due to their poor pharmacokinetics. Using nanoparticles as carriers can improve this because their large size reduces clearance and improves retention within tumors, but it also slows

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