761982

Dibenzocyclooctyne-PEG4-alcohol

for Copper-free Click Chemistry

• Synonym(s): Polyethylene glycol, DBCO-PEG4-OH
• Empirical Formula (Hill Notation): C₂₉H₃₆N₂O₆
• Molecular Weight: 508.61
• UNSPSC Code: 51171641
• PubChem Substance ID: 329766594
• NACRES: NA.22

Properties

• Quality Segment: 100
• form: solid
• reaction suitability: reaction type: click chemistry, reagent type: linker
• mp: 50-60 °C
• functional group: hydroxyl
• storage temp.: −20°C
• SMILES string: O=C(CCCCC(NCCOCCOCCOCCOCCO)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
• InChI: 1S/C29H36N2O6/c32-16-18-36-20-22-37-21-19-35-17-15-30-28(33)11-5-6-12-29(34)31-23-26-9-2-1-7-24(26)13-14-25-8-3-4-10-27(25)31/h1-4,7-10,32H,5-6,11-12,15-23H2,(H,30,33)
• InChI key: ZZXWONCQAFVJHM-UHFFFAOYSA-N

Description

Application

Alcohol functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable