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764698

Sigma-Aldrich

Poly(L-lactide)

average Mn 20,000, PDI ≤1.1

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Synonym(s):
PLA, PLLA, Polylactide, L-Lactide polymer, PLA, Poly(L-Lactic acid)
Linear Formula:
H(C3H4O2)nOCH3
NACRES:
NA.23

form

solid

optical activity

[α]22/D -153°, c = 0.5% in chloroform

mol wt

average Mn 20,000

degradation timeframe

>3 years

transition temp

Tm 167-172 °C

PDI

≤1.1

storage temp.

2-8°C

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This Item
76511276459095468
Poly(L-lactide) average Mn 20,000, PDI ≤1.1

Sigma-Aldrich

764698

Poly(L-lactide)

Poly(L-lactide) average Mn 10,000, PDI ≤1.1

Sigma-Aldrich

765112

Poly(L-lactide)

Poly(L-lactide) average Mn 5,000, PDI ≤1.2

Sigma-Aldrich

764590

Poly(L-lactide)

Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

optical activity

[α]22/D -153°, c = 0.5% in chloroform

optical activity

[α]22/D -150°, c = 0.5% in chloroform

optical activity

[α]22/D -147°, c = 0.5% in chloroform

optical activity

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mol wt

average Mn 20,000

mol wt

average Mn 10,000

mol wt

average Mn 5,000

mol wt

Mn 103,000, Mw 259,000

degradation timeframe

>3 years

degradation timeframe

>3 years

degradation timeframe

>3 years

degradation timeframe

>3 years

General description

Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

Application

Used in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.

Features and Benefits

High initial strength, good strength retention and high amount of crystallinity as much as 70% which in turn is responsible for the very slow degradation rate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

Poly(D-lactide) inherent viscosity ~1.2 dl/g

Sigma-Aldrich

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Poly(D-lactide)

vibrant-m

GF45989881

Polylactic Acid - Biopolymer

Poly(D,L-lactide) acid terminated, average Mw 15000

Sigma-Aldrich

805734

Poly(D,L-lactide)

Synthesis and thermal properties of novel star-shaped poly (l-lactide)s with starburst PAMAM-OH dendrimer macroinitiator.
Zhao, Y. L., Cai, Q., Jiang, J., Shuai, X. T., Bei, J. Z., Chen, C. F., & Xi, F.
Polymer, 43(22), 5819-5825 (2002)
Chemical synthesis of polylactide and its copolymers for medical applications
Bendix, D.
Polymer Degradation and Stability, 59(1), 129-135 (1998)
Effect of poly (ethylene glycol)-block- poly (L-lactide) on the poly [(R)-3-hydroxybutyrate]/poly (L-lactide) blends
Yoon, J. S., Lee, W. S., Kim, K. S., Chin, I. J., Kim, M. N., & Kim, C.
Eur. Polymer J., 36(2), 435-442 (2000)
Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)

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