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765112

Sigma-Aldrich

Poly(L-lactide)

average Mn 10,000, PDI ≤1.1

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Synonym(s):
PLA, PLLA, Polylactide, L-Lactide polymer, PLA, Poly(L-Lactic acid)
Linear Formula:
H(C3H4O2)nOCH3
NACRES:
NA.23

form

solid

Quality Level

optical activity

[α]22/D -150°, c = 0.5% in chloroform

mol wt

average Mn 10,000

degradation timeframe

>3 years

transition temp

Tm 162-167 °C

PDI

≤1.1

storage temp.

2-8°C

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This Item
7646989546881273
Poly(L-lactide) average Mn 10,000, PDI ≤1.1

Sigma-Aldrich

765112

Poly(L-lactide)

Poly(L-lactide) average Mn 20,000, PDI ≤1.1

Sigma-Aldrich

764698

Poly(L-lactide)

Poly(L-lactide) viscosity ~4.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

95468

Poly(L-lactide)

Poly(L-lactide) viscosity ~2.0 dL/g, 0.1 % (w/v) in chloroform(25 °C)

Sigma-Aldrich

81273

Poly(L-lactide)

optical activity

[α]22/D -150°, c = 0.5% in chloroform

optical activity

[α]22/D -153°, c = 0.5% in chloroform

optical activity

-

optical activity

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

mol wt

average Mn 10,000

mol wt

average Mn 20,000

mol wt

Mn 103,000, Mw 259,000

mol wt

Mw ~260,000

degradation timeframe

>3 years

degradation timeframe

>3 years

degradation timeframe

>3 years

degradation timeframe

>3 years

transition temp

Tm 162-167 °C

transition temp

Tm 167-172 °C

transition temp

-

transition temp

-

General description

Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

Application

Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.

Features and Benefits

High initial strength, good strength retention and high amount of crystallinity, as much as 70%, which in turn is responsible for the very slow degradation rate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Customers Also Viewed

Slide 1 of 8

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Synthesis and thermal properties of novel star-shaped poly (l-lactide)s with starburst PAMAM-OH dendrimer macroinitiator.
Zhao, Y. L., Cai, Q., Jiang, J., Shuai, X. T., Bei, J. Z., Chen, C. F., & Xi, F.
Polymer, 43(22), 5819-5825 (2002)
Chemical synthesis of polylactide and its copolymers for medical applications
Bendix, D.
Polymer Degradation and Stability, 59(1), 129-135 (1998)
Effect of poly (ethylene glycol)-block- poly (L-lactide) on the poly [(R)-3-hydroxybutyrate]/poly (L-lactide) blends
Yoon, J. S., Lee, W. S., Kim, K. S., Chin, I. J., Kim, M. N., & Kim, C.
Eur. Polymer J., 36(2), 435-442 (2000)
Wolf, Florian F.; et al.
Macromolecules, 42, 5622-5628 (2009)
Zhang, Wen-Bin; et al.
Macromolecules, 44, 2589-2596 (2011)

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