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900554

Sigma-Aldrich

Gold coated glass slide

layer thickness 100 nm , gold, size 75 mm × 25 mm × 1 mm

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Synonym(s):
Fluorescence enhancing gold substrates, Plasmonic gold slides, Raman enhancing substrates, pGOLD slide
Linear Formula:
Au
CAS Number:
Molecular Weight:
196.97
MDL number:

Quality Level

layer thickness

100 nm , gold

size

75 mm × 25 mm × 1 mm

refractive index

n20/400 1.52 (lit.)

particle size

~100 nm (APS)

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

  • Vis-IR extinction-peak wavelength: 580-620 nm.
  • Vis-IR extinction-peak OD: 0.6-0.9
  • Vis-IR extinction-peak OD-average: 0.6-0.8.
  • Vis-IR extinction-peak OD-intraslide CV: <15%.
  • Fluorescence enhancement: >50 times at 800 nm.

Application

Our gold coated slides contain ~100 nm thick film of nanostructured plasmonic gold particles and find applications as fluorescence enhancing substrates for many fluorophores emitting in the 600-1700 nm range, including Cy5, Alexa Fluor 647, IRDye® 800 and others. These gold substrates can also be used to enhance Raman scattering signals. Using these slides an enhancement in Raman signal up to 100-fold can be achieved at ~800 nm emission channel. A 5-10 fold increase in scattering can be obtained in the visible light range. These slides are also capable of enhancing surface Raman scattering signals up to 107 fold.

Other Notes

Quantity: 5 slides (per 1EA).

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
IRDye is a registered trademark of LI-COR, Inc.
pGOLD is a trademark of Nirmidas Biotech, Inc

Storage Class

13 - Non Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Bo Zhang et al.
Nature medicine, 20(8), 948-953 (2014-07-21)
Type 1 diabetes (T1D) is an autoimmune disease, whereas type 2 diabetes (T2D) results from insulin resistance and beta cell dysfunction. Previously, the onset of these two separate diseases was easily distinguished, with children being most at risk for T1D
Scott M Tabakman et al.
Nature communications, 2, 466-466 (2011-09-15)
Protein chips are widely used for high-throughput proteomic analysis, but to date, the low sensitivity and narrow dynamic range have limited their capabilities in diagnostics and proteomics. Here we present protein microarrays on a novel nanostructured, plasmonic gold film with
Xiaoyang Li et al.
Journal of clinical microbiology, 54(7), 1726-1733 (2016-03-25)
Toxoplasmosis is an infection caused by the protozoan parasite Toxoplasma gondii that can lead to severe sequelae in the fetus during pregnancy. Definitive serologic diagnosis of the infection during gestation is made mostly by detecting T. gondii-specific antibodies, including IgG
Near-infrared-fluorescence-enhanced molecular imaging of live cells on gold substrates.
Guosong Hong et al.
Angewandte Chemie (International ed. in English), 50(20), 4644-4648 (2011-04-21)

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