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Key Documents

904465

Sigma-Aldrich

Silica

monodisperse, non-porous, 2.0 μm

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silica, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
Molecular Weight:
60.08
MDL number:
UNSPSC Code:
41123003
NACRES:
NA.23

form

powder

bp

2230 °C (lit.)

mp

>1600 °C (lit.)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Application

Monodisperse nonporous silica nanoparticles find application in drug delivery and molecular imaging whereas micron sized particles are used in liquid chromatography. We offer highly monodisperse(coefficient of variance <10%) nonporous silica in size varying from 150 nm to 50 μm. The high monodispersity of our particles makes them suitable for aforementioned applications.
Silica monodispersed, non-porous (2 μm) is a micro-sized filler material can be used as a spacer in liquid crystals, high performance liquid chromatography (HPLC), and nanomedicine for biological applications.

Storage Class

11 - Combustible Solids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Practical Examination of a Nonporous Silica Stationary Phase for Reversed-Phase Fast LC Applications
D R Jenke
Journal of Chromatographic Science, 34, 362-362 (1996)
Size control of monodisperse nonporous silica particles by seed particle growth
Zhao B, et al.
Particuology, 9(3), 314-317 (2011)
In-depth characterization of slurry packed capillary columns with 1.0-mm nonporous particles using reversed-phase isocratic ultrahigh-pressure liquid chromatography
Patel KD, et al.
Analytical Chemistry, 76(19), 5777-5786 (2004)
Nonporous silica nanoparticles for nanomedicine application
Tang L and Cheng J
Nano Today, 8(3), 290-312 (2013)
Martha Kim et al.
Scientific reports, 7(1), 8238-8238 (2017-08-16)
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in

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